CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009152
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 33B 
Protein Synonyms/Alias
  
Gene Name
 Vps33b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
19LPDFSMLKRLARDQLubiquitination[1]
419PKDYRSLKTQYLQSYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes (By similarity). 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).  
Keyword
 Acetylation; Complete proteome; Endosome; Lysosome; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 617 AA 
Protein Sequence
MAFPHRLDAP ELPDFSMLKR LARDQLIYLL EQLPGKKDLF IEADLMSPLD RIANVSILKQ 60
HEVDKLYKVE NKPALSANEQ LCFLVRPRIK NMRYIASLVN ADKLAGRIRK YKVILSPQKF 120
YACEMVLEEE GVYGDVSCDE WAFSLLPLDV DLLSMELPEF FRDYFLEGDQ RWINTVAQAL 180
HLLSTLYGPF PNCYGIGRCA KMSYDLWRKL EEEEDSETKG RKPEIGHIFL LDRDVDFVTA 240
LCSQVVYEGL VDDTFRIKCG SVDFGPEVTS SDKSLKVLLN AEDKVFSEIR NEHFSNVFGF 300
LSQKARNLQA QYDRRRGMDI KQMKNFVSQE LKGLKQEHRL LSLHIGACES IMKKKTKQDF 360
QELIKTEHAL LEGFNIREST SYIEEHIDRQ VSPIESLRLM CLLSITENGL IPKDYRSLKT 420
QYLQSYGPEH LLTFSNLRRA GLLTEQAPGD TLTAVESKVS KLVTDKAAGK ITDAFSSLAK 480
RSNFRAISKK LNLIPRVDGE YDLKVPRDMA YVFSGAYVPL SCRIIEQVLD RRSWQGLDEV 540
VRLLNCSEFA FTDTAKEDKA SSESLRLILV VFLGGCTFSE ISALRFLGRE KGYRFIFLTT 600
AVTNSARLME AMSEVKS 617 
Gene Ontology
 GO:0030897; C:HOPS complex; IEA:Compara.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0031091; C:platelet alpha granule; IEA:Compara.
 GO:0006944; P:cellular membrane fusion; IEA:Compara.
 GO:0032418; P:lysosome localization; IEA:Compara.
 GO:0032400; P:melanosome localization; IEA:Compara.
 GO:0070889; P:platelet alpha granule organization; IEA:Compara.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; ISA:MGI. 
Interpro
 IPR027482; Sec-1-like_dom2.
 IPR001619; Sec1-like.
 IPR027121; VPS33. 
Pfam
 PF00995; Sec1 
SMART
  
PROSITE
  
PRINTS