| Tag | Content |
|---|
| CPLM ID | CPLM-020757 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein-cysteine N-palmitoyltransferase HHAT-like protein |
Protein Synonyms/Alias | Glycerol uptake/transporter homolog; Hedgehog acyltransferase-like protein |
Gene Name | Hhatl |
Gene Synonyms/Alias | Gup1; Kiaa1173 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 501 | EQRQDREKLE***** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN. |
Sequence Annotation | |
Keyword | Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 503 AA |
Protein Sequence | MGIKTALPAA ELGLYSLVLS GALAYAGRGL LEASQDGAHR KAFRESVRPG WEYLGRKMDV 60
ADFEWVMWFT NFRNVIVFAL SGHVLFAKLC TMVAPQLRSW MYAVYGVLAV VGTMGPWYLL 120
LLLGHCMVLY VASLLGQRWL CLALGLASLA SFKVDPGISW QSGFVTGTFD LQDVLFHGGS 180
SFTVLRCTSF ALESCAHPDR RYSLADLLKY NFYLPFFFFG PIMTFDRFHA QVSQEPVRPE 240
GELWHIQAQA GLSAAAIVAV DVFFHFFYIL TIPSDLKFAS RLPDSALAGL AYSNLVYDWV 300
KAAVLFGVVN TVARLDHLDP PQPPKCITAL YVFGETHFDR GINDWLCKYV YDHIGGDHST 360
VIPELAASVA TFVVTTLWLG PCDIVYLWSV LNCFGLNFEL WVQKLAERGP LAQIEARLSE 420
QMSRRVRALC GAVNFWAIIM YNLVSLNSLE FTELVARRLI LTGFPQTTLA VLFVTYCGVQ 480
LVKERERSLA LEEEQRQDRE KLE 503 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara. GO:0060262; P:negative regulation of N-terminal protein palmitoylation; IDA:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |