| Tag | Content |
|---|
| CPLM ID | CPLM-024118 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Connector enhancer of kinase suppressor of ras 2 |
Protein Synonyms/Alias | Connector enhancer of KSR 2; CNK homolog protein 2; CNK2; Membrane-associated guanylate kinase-interacting protein; Maguin |
Gene Name | Cnksr2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 342 | STISTPTKRDSSALQ | ubiquitination | [1] | | 982 | DNPDLTSKEFQQWKQ | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | May function as an adapter protein or regulator of Ras signaling pathways, in synaptic junctions. |
Sequence Annotation | DOMAIN 11 76 SAM.
DOMAIN 84 178 CRIC.
DOMAIN 215 297 PDZ.
DOMAIN 332 515 DUF1170.
DOMAIN 570 669 PH.
MOD_RES 248 248 Phosphoserine (By similarity).
MOD_RES 325 325 Phosphoserine (By similarity).
MOD_RES 390 390 Phosphoserine (By similarity).
MOD_RES 467 467 Phosphoserine (By similarity).
MOD_RES 846 846 Phosphothreonine (By similarity).
MOD_RES 906 906 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Membrane; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1032 AA |
Protein Sequence | MALIMEPVSK WSPSQVVDWM KGLDDCLQQY IKNFEREKIS GDQLLRITHQ ELEDLGVSRI 60
GHQELILEAV DLLCALNYGL ETENLKTLSH KLNASAKNLQ NFITGRRRSG HYDGRTSRKL 120
PNDFLTSVVD LIGAAKSLLA WLDRSPFAAV TDYSVTRNNV IQLCLELTTI VQQDCTVYET 180
ENKILHVCKT LSGVCDHIIS LSSDPLVSQS AHLEVIQLAN IKPSEGLGMY IKSTYDGLHV 240
ITGTTENSPA DRCKKIHAGD EVIQVNHQTV VGWQLKNLVN ALREDPSGVI LTLKKRPQSM 300
LTSAPALLKN MRWKPLALQP LIPRSPTSSV ATPSSTISTP TKRDSSALQD LYIPPPPAEP 360
YIPRDEKGNL PCEDLRGHMV GKPVHKGSES PNSFLDQEYR KRFNIVEEDT VLYCYEYEKG 420
RSSSQGRRES TPTYGKLRPI SMPVEYNWVG DYEDPNKMKR DSRRENSLLR YMSNEKIAQE 480
EYMFQRNSKK DTGKKSKKKG DKSTSPTHYS LLPSLQMDAL RQDIMGTPVP ETTLYHTFQQ 540
SSLQHKSKKK NKGAIAGKSK RRISCKDLGR GDCEGWLWKK KDAKSYFSQK WKKYWFVLKD 600
ASLYWYINEE DEKAEGFISL PEFKIDRASE CRKKYAFKAC HPKIKSFYFA AEHLDDMNRW 660
LNRINMLTAG YAERERIKQE QDYWSESDKE EADTPSTPKQ DSPPPPYDTY PRPPSMSCAS 720
PYVEAKHSRL SSTETSQSQS SHEEFRQEVT GSSAVSPIRK TASQRRSWQD LIETPLTSSG 780
LHYLQTLPLE DSVFSDSAAI SPEHRRQSTL PTQKCHLQDH YGPYPLAESE RMQVLNGNGG 840
KPRSFTLPRD SGFNHCCLNA PVSACDPQDD IQPPEVEEEE EEEEEEAAGE NIGEKNENRE 900
EKLGDSLQDL YRALEEASLS PLGEHRISTK IEYKLSFIKR CNDPVMNEKL HRLRILKSTL 960
KAREGEVAII DKVLDNPDLT SKEFQQWKQM YLDLFLDICQ NTTSNDPLSI SSEVDVITSS 1020
LTHTHSYIET HV 1032 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |