CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044517
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Desmoglein-2 
Protein Synonyms/Alias
  
Gene Name
 DSG2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
195EPNTLNSKISYRIVSubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 232 AA 
Protein Sequence
MARSPGRAYA LLLLLICFNV GSGLHLQVLS TRNENKLLPK HPHLVRQKRA WITAPVALRE 60
GEDLSKKNPI AKIHSDLAEE RGLKITYKYT GKGITEPPFG IFVFNKDTGE LNVTSILDRE 120
ETPFFLLTGY ALDARGNNVE KPLELRIKVL DINDNEPVFT QDVFVGSVEE LSAAHTLVMK 180
INATDADEPN TLNSKISYRI VSLEPAYPPV FYLNKDTGEI YTTSVTLDRE VS 232 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR009122; Desmosomal_cadherin. 
Pfam
 PF00028; Cadherin 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.