CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019328
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DDRGK domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 DDRGK1 
Gene Synonyms/Alias
 C20orf116 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
227INYIKQSKVVLLEDLubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 DOMAIN 229 273 PCI.
 CROSSLNK 267 267 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Isopeptide bond; Polymorphism; Reference proteome; Signal; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 314 AA 
Protein Sequence
MVAPVWYLVA AALLVGFILF LTRSRGRAAS AGQEPLHNEE LAGAGRVAQP GPLEPEEPRA 60
GGRPRRRRDL GSRLQAQRRA QRVAWAEADE NEEEAVILAQ EEEGVEKPAE THLSGKIGAK 120
KLRKLEEKQA RKAQREAEEA EREERKRLES QREAEWKKEE ERLRLEEEQK EEEERKAREE 180
QAQREHEEYL KLKEAFVVEE EGVGETMTEE QSQSFLTEFI NYIKQSKVVL LEDLASQVGL 240
RTQDTINRIQ DLLAEGTITG VIDDRGKFIY ITPEELAAVA NFIRQRGRVS IAELAQASNS 300
LIAWGRESPA QAPA 314 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB. 
Interpro
 IPR019153; DDRGK_dom-contain. 
Pfam
 PF09756; DDRGK 
SMART
  
PROSITE
  
PRINTS