CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011459
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 33B 
Protein Synonyms/Alias
 Zinc finger protein 11B; Zinc finger protein KOX2 
Gene Name
 ZNF33B 
Gene Synonyms/Alias
 KOX2; ZNF11B 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
355QRVHTGEKHFQCNQCacetylation[1]
364FQCNQCGKTFWEKSNacetylation[1]
383QRSHTGEKPFECNECacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 12 83 KRAB.
 ZN_FING 329 351 C2H2-type 1.
 ZN_FING 357 379 C2H2-type 2.
 ZN_FING 385 407 C2H2-type 3.
 ZN_FING 413 435 C2H2-type 4.
 ZN_FING 441 463 C2H2-type 5.
 ZN_FING 469 491 C2H2-type 6.
 ZN_FING 497 519 C2H2-type 7.
 ZN_FING 525 547 C2H2-type 8.
 ZN_FING 553 575 C2H2-type 9.
 ZN_FING 581 603 C2H2-type 10.
 ZN_FING 609 631 C2H2-type 11.
 ZN_FING 637 659 C2H2-type 12.
 ZN_FING 665 687 C2H2-type 13.
 ZN_FING 693 715 C2H2-type 14.
 ZN_FING 721 743 C2H2-type 15.
 ZN_FING 749 771 C2H2-type 16.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 778 AA 
Protein Sequence
MNKVDQKFQG SVSFKDVTVG FTQEEWQHLD PSQRALYRDV MLENYSNLVS VGYCAHKPEV 60
IFRLEQGEEP WRLEEEFPSQ SFPEVWTADH LKERSQENQS KHLWEVVFIN NEMLTKEQGN 120
VIGIPFNMDV SSFPSRKMFC QYDSRGMSFN TVSELVISKI NYLGKKSDEF NACGKLLLNI 180
KHDETHTREK NEVLKNRNTL SHRENTLQHE KIQTLDHNFE YSICQETLLE KAVFNTRKRE 240
NAEENNCDYN EFGRTFCDSS SLLFHQIPPS KDSHYEFSDC EKFLCVKSTL SKHDGVPVKH 300
YDCGESGNNF RRKLCLSQLQ KGDKGEKHFE CNECGKAFWE KSHLTRHQRV HTGEKHFQCN 360
QCGKTFWEKS NLTKHQRSHT GEKPFECNEC GKAFSHKSAL TLHQRTHTGE KPYQCNACGK 420
TFYQKSDLTK HQRTHTGQKP YECYECGKSF CMNSHLTVHQ RTHTGEKPFE CLECGKSFCQ 480
KSHLTQHQRT HIGDKPYECN ACGKTFYHKS VLTRHQIIHT GLKPYECYEC GKTFCLKSDL 540
TIHQRTHTGE KPFACPECGK FFSHKSTLSQ HYRTHTGEKP YECHECGKIF YNKSYLTKHN 600
RTHTGEKPYE CNECGKTFCQ KSQLTQHQRI HIGEKPYECN ECGKAFCHKS ALIVHQRTHT 660
QEKPYKCNEC GKSFCVKSGL ILHERKHTGE KPYECNECGK SFSHKSSLTV HHRAHTGEKS 720
CQCNECGKIF YRKSDLAKHQ RSHTGEKPYE CNTCRKTFSQ KSNLIVHQRT HIGEKPYE 778 
Gene Ontology
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS