| Tag | Content |
|---|
| CPLM ID | CPLM-011684 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 3 subunit B |
Protein Synonyms/Alias | eIF3b; Eukaryotic translation initiation factor 3 subunit 9 |
Gene Name | eIF3-S9 |
Gene Synonyms/Alias | CG4878 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 74 | VEPVRLEKLKLVINK | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. |
Sequence Annotation | DOMAIN 57 141 RRM.
REPEAT 207 246 WD 1.
REPEAT 293 331 WD 2.
REPEAT 334 369 WD 3.
REPEAT 442 484 WD 4.
REPEAT 530 575 WD 5. |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome; Repeat; RNA-binding; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 690 AA |
Protein Sequence | MAKKKSEEHS GTDANDSDYQ EEPNFDDPPG FVDNISDEDL LGDMLAQRPS EADGVESVVV 60
VDNIPKVEPV RLEKLKLVIN KLFSNYGEIV NVVYPVDEEG KTKGYAFMEY KQARQAEEAV 120
KKLNNHRLDK NHTFAVNLFT DFQKYENIPE KWEPPTVQTF KVQSDLYNFI NDPDTYDQYC 180
VAAETAPNCV QVGFWQNVLP EPFELETRER FTDTFVKWSP LGTYVVTFHK PGVAIWGGSS 240
FQKIQKFPHP GTQFVEFSPC ENYLVTYGPT PTGQKIIIWD IRTGAEKRSF VADGMSVLSM 300
FRWSHDDKFV ARMGENSIHI YETPSFYLLD LKSIKIPGIR GFSWSPTDNV IAYWVEEQNQ 360
IPARVTLMEI PKKREIRNKN LFHVADCKLH WQKSGDYLCV KVDRYSKLKK DKKDLDVKFL 420
GMFYNFEIFH MREKEIPVDS VEIRELILAF AWEPVGNKFS IIHGETNSSN VSFYEVNKGV 480
KPSLVKRLEK KSCTHLFWSP RGQFIVMANL TMGTFEFVDS TNDYIITASP DHFRASEVEW 540
DPTGRYVVTG VSSWKVKEDT GFNMYTFQGR IIKRTILKNF VQFLWRPRPP TLLSEEKQKE 600
IKKNLKKYYA AFEQKDRLRL TRASKELLEK RSQLRETFME YRNKRIAEWA EQKSRRIMLR 660
GHVDTDNLET DEVDEEIVEF LVKEEVTLLE 690 |
Gene Ontology | GO:0005829; C:cytosol; ISS:FlyBase. GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP. GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP. GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:UniProtKB. GO:0003729; F:mRNA binding; ISS:FlyBase. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003743; F:translation initiation factor activity; ISS:UniProtKB. GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP. GO:0006446; P:regulation of translational initiation; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |