| Tag | Content |
|---|
| CPLM ID | CPLM-026029 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribonucleoside-diphosphate reductase |
Protein Synonyms/Alias | |
Gene Name | GK0911 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Geobacillus kaustophilus (strain HTA426) |
NCBI Taxa ID | 235909 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | IIIDDQGKPVSFSRE | acetylation | [1] | | 221 | LMVNEPPKRRLELVK | acetylation | [1] | | 228 | KRRLELVKEAYWALS | acetylation | [1] | | 441 | VPAIEVMKSIMRSQL | acetylation | [1] | | 497 | VMKRQYVKDGMIIIE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus. Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG. Proteomics. 2013 Aug;13(15):2278-82. [ PMID: 23696451] |
Functional Description | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; DNA replication; Oxidoreductase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 785 AA |
Protein Sequence | MPFFRLSFHP LACPSGFFIE GVGKRMTALT KMIIIDDQGK PVSFSREEFA SLIGQAVAGF 60
GRLSLDEYVE RVWQLLSRKE SVTVEQLHQT AILEGLSYID EDEPDWTFVC ARLYLQQLYR 120
EAARQRGYDA RERYGDFYSL IVSLTEQGVY SPLLLERYTK EEIETAGSFL DPGKDLLFTY 180
IGLRTLADRY LARDYERRLY ELPQERFLVI AMTLMVNEPP KRRLELVKEA YWALSNLYMT 240
VATPTLANAG KSYGQLSSCF VDTVDDSLQG IYDSNTDIAN LSKSGGGIGV YLGKIRSRGS 300
DIKGFKGVSS GVIPWMKQLN NTAVSVDQLG QRKGAISVYL DVWHKDIFAF LDARLNNGDE 360
RLRTHDLFTG VCIPDLFMEQ VEQRGDWYLF DPHEVRKVMG FSLEDFYDEE KGCGSFREKY 420
WQCVNEPRLS KEKVPAIEVM KSIMRSQLES GTPFMFYRDE VNRQNPNRHL GMIYCSNLCT 480
EIAQNQSPTV MKRQYVKDGM IIIEKIPGDF VVCNLSSINL ARAVTDGVLA RLIPIQMRML 540
DNVIDLNNIP VLQAGLTNEK YRAVGLGTFG WHHLLALKGI RWESEEAVRY ADELYETIAY 600
LAIQASMELA KEKGSYPAFP GSDWQTGAYF ERRGYQSHGE LDWDRLKQDV ARYGMRNGYI 660
MAIAPNASTS IIAGSTASID PIFLKVYAEE KKDYKIPVTV PDLNEQTTWY YKSAYHIDQR 720
WSIKQNAARQ RHIDQAISFN FYVMNTIKAK ELLDLHLTAW KSGLKTTYYV RSTSGTIDEC 780
DSCAS 785 |
Gene Ontology | GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro. GO:0005524; F:ATP binding; IEA:InterPro. GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC. GO:0006260; P:DNA replication; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |