CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012432
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 132D 
Protein Synonyms/Alias
 Mature oligodendrocytes transmembrane protein; Mature OL transmembrane protein 
Gene Name
 TMEM132D 
Gene Synonyms/Alias
 HBE120; KIAA1944; MOLT 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
128NKFSLNWKLKAHILRubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 May serve as a cell-surface marker for oligodendrocyte differentiation. 
Sequence Annotation
 CARBOHYD 505 505 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1099 AA 
Protein Sequence
MCPSEMGTLW HHWSPVLISL AALFSKVTEG RGILESIQRF SLLPTYLPVT YHINNADVSF 60
FLKEANQDIM RNSSLQSRVE SFLIYKSRRL PVLNASYGPF SIEQVVPQDL MLPSNPFGFT 120
NKFSLNWKLK AHILRDKVYL SRPKVQVLFH IMGRDWDDRS AGEKLPCLRV FAFRETREVR 180
GSCRLQGDLG LCVAELELLS SWFSPPTVVA GRRKSVDQPE GTPVELYYTV HPGGERGDCV 240
REDARRSNGI RTGHSDIDES GPPLQRIGSI FLYQTHRKPS LRELRLDNSV AIHYIPKTVR 300
KGDVLTFPVS ISRNSTEDRF TLRAKVKKGV NIIGVRASSP SIWDVKERTD YTGKYAPAVI 360
VCQKKAAGSE NSADGASYEV MQIDVEVEEP GDLPATQLVT WQVEYPGEIT SDLGVSKIYV 420
SPKDLIGVVP LAMEAEILNT AILTGKTVAV PVKVVSVEDD GTVTELLESV ECRSSDEDVI 480
KVSDRCDYVF VNGKEMKGKV NVVVNFTYQH LSSPLEMTVW VPRLPLQIEV SDTELNQIKG 540
WRVPIVSSRR PAGDSEEEED DERRGRGCTL QYQHAMVRVL TQFVAEAAGP GGHLAHLLGS 600
DWQVDITELI NDFMQVEEPR IAKLQGGQIL MGQELGMTTI QILSPLSDTI LAEKTITVLD 660
EKVTITDLGV QLVTGLSLSL QLSPGSNRAI FATAVAQELL QRPKQEAAIS CWVQFSDGSV 720
TPLDIYDGKD FSLMATSLDE KVVSIHQDPK FKWPIIAAET EGQGTLVKVE MVISESCQKS 780
KRKSVLAVGT ANIKVKFGQN DANPNTSDSR HTGAGVHMEN NVSDRRPKKP SQEWGSQEGQ 840
YYGSSSMGLM EGRGTTTDRS ILQKKKGQES LLDDNSHLQT IPSDLTSFPA QVDLPRSNGE 900
MDGNDLMQAS KGLSDLEIGM YALLGVFCLA ILVFLINCVT FALKYRHKQV PFEEQEGMSH 960
SHDWVGLSNR TELLENHINF ASSQDEQITA IDRGMDFEES KYLLSTNSQK SINGQLFKPL 1020
GPIIIDGKDQ KSEPPTSPTS KRKRVKFTTF TAVSSDDEYP TRNSIVMSSE DDIKWVCQDL 1080
DPGDCKELHN YMERLHENV 1099 
Gene Ontology
 GO:0016021; C:integral to membrane; NAS:UniProtKB.
 GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. 
Interpro
 IPR026307; TMEM132. 
Pfam
  
SMART
  
PROSITE
  
PRINTS