UniProt Accession

 PFD2_RAT; B0BN18 

Genbank Protein ID

 BC158649 

Genbank Nucleotide ID

 AAI58650.1 

Protein Name

 Prefoldin subunit 2 

Protein Synonyms/Alias

  

Gene Name

 Pfdn2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
99	GNKEQIQKIIETLSQ	acetylation	[1]
132	RLMGEDEKPAAKENS	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity). 

Sequence Annotation

  

Keyword

 Chaperone; Complete proteome; Cytoplasm; Mitochondrion; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 154 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016272; C:prefoldin complex; IEA:InterPro.
 GO:0006457; P:protein folding; IEA:Compara. 

Interpro

 IPR027235; PFD2.
 IPR002777; PFD_beta-like.
 IPR009053; Prefoldin. 

Pfam

 PF01920; Prefoldin_2 

SMART

  

PROSITE

  

PRINTS