CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027081
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 L-fucose kinase 
Protein Synonyms/Alias
 Protein Fuk 
Gene Name
 Fuk 
Gene Synonyms/Alias
 FuK 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
557FFCQALQKARHVLEAubiquitination[1]
994TSYWEQKKLMAPGCEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1090 AA 
Protein Sequence
MEQSEGVNWT VIILTCQYKD SVQVFQRELE VRQRREQIPA GTMLLAVEDP QTRVGSGGAT 60
LNALLVAAEH LSARAGFTVV TSDVLHSAWI LILHMGRDFP FDDCGRAFTC LPVENPQAPV 120
EALVCNLDCL LDIMTHRLGP GSPPGVWVCS TDMLLSVPPN PGISWDGFRG ARVIAFPGSL 180
AYALNHGVYL TDSQGLVLDI YYQGTKAEIQ RCVGPDGLVP LVSGVVFFSV ETAEHLLATH 240
VSPPLDACTY MGLDSGAQPV QLSLFFDILL CMARNMSREN FLAGRPPELG QGDMDVASYL 300
KGARAQLWRE LRDQPLTMVY VPDGGYSYMT TDATEFLHRL TMPGVAVAQI VHSQVEEPQL 360
LEATCSVVSC LLEGPVHLGP RSVLQHCHLR GPIRIGAGCF VSGLDTAHSE ALHGLELHDV 420
ILQGHHVRLH GSLSRVFTLA GRLDSWERQG AGMYLNMSWN EFFKKTGIRD WDLWDPDTPP 480
SDRCLLTARL FPVLHPTRAL GPQDVLWMLH PRKHRGEALR AWRASWRLSW EQLQPCVDRA 540
ATLDFRRDLF FCQALQKARH VLEARQDLCL RPLIRAAVGE GCSGPLLATL DKVAAGAEDP 600
GVAARALACV ADVLGCMAEG RGGLRSGPAA NPEWIQPFSY LECGDLMRGV EALAQEREKW 660
LTRPALLVRA ARHYEGAEQI LIRQAVMTAR HFVSTQPVEL PAPGQWVVTE CPARVDFSGG 720
WSDTPPIAYE LGGAVLGLAV RVDGRRPIGA KARRIPEPEL WLAVGPRQDE MTMRIVCRSL 780
DDLRDYCQPH APGALLKAAF ICAGIVHLHS ELPLLEQLLH SFNGGFELHT WSELPHGSGL 840
GTSSILAGAA LAALQRAAGR AVGTEALIHA VLHLEQVLTT GGGWQDQVSG LMPGIKVGRS 900
RAQLPLKVEV EEITVPEGFV QKINDHLLLV YTGKTRLARN LLQDVLRNWY ARLPVVVQNA 960
RRLVRQTEKC AEAFRQGNLP LLGQYLTSYW EQKKLMAPGC EPLAVQRMMD VLAPYAYGQS 1020
LAGAGGGGFL YLLTKEPRQK ETLEAVLAKA EGLGNYSVHL VEVDPQGLSL QLLGHDTRLC 1080
GAGPSEVGTT 1090 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0050201; F:fucokinase activity; IEA:EC. 
Interpro
 IPR012887; Fucokinase.
 IPR013750; GHMP_kinase_C_dom.
 IPR006204; GHMP_kinase_N_dom.
 IPR006206; Mevalonate/galactokinase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 
Pfam
 PF07959; Fucokinase
 PF08544; GHMP_kinases_C
 PF00288; GHMP_kinases_N 
SMART
  
PROSITE
  
PRINTS
 PR00959; MEVGALKINASE.