CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029779
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Chromatin modification-related protein MEAF6 
Protein Synonyms/Alias
 Chromosome 1 open reading frame 149, isoform CRA_f 
Gene Name
 MEAF6 
Gene Synonyms/Alias
 C1orf149; hCG_25685 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47DRYLTNQKNSNSKNDacetylation[1, 2, 3]
52NQKNSNSKNDRRNRKacetylation[2, 3]
69EAERLFSKSSVTSAAacetylation[1]
91VQDQLIEKREPGSGTubiquitination[4]
129DGSVQGVKPQKAASSacetylation[2]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
MSLFFISQET LANLERQIYA FEGSYLEDTQ MYGNIIRGWD RYLTNQKNSN SKNDRRNRKF 60
KEAERLFSKS SVTSAAAVSA LAGVQDQLIE KREPGSGTES DTSPDFHNQE NEPSQEDPED 120
LDGSVQGVKP QKAASSTSSG SHHSSHKKRK NKNRHRIDLK LNKKPRADY 169 
Gene Ontology
 GO:0005813; C:centrosome; IDA:HPA.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR015418; Hist_AcTrfase_NuA4_cplx. 
Pfam
 PF09340; NuA4 
SMART
  
PROSITE
  
PRINTS