UniProt Accession

 JKAMP_HUMAN; Q9P055; B4DP67; Q6FIB6; Q6IAJ2; Q7Z5D4; Q86SY6; Q9H0Q6; Q9H2W0; Q9HAH5; Q9P0R3 

Genbank Protein ID

 AF529304; AF151047; AF161445; AL136696; AK021683; AK027591; AK298209; AF212245; BX161501; CR457163; CR533510; CH471061; BC005198; BC010359 

Genbank Nucleotide ID

 AAP85636.1; AAF36133.1; AAF29005.1; CAB66631.1; BAB13874.1; BAB55216.1; BAG60479.1; AAG41781.1; CAD61945.1; CAG33444.1; CAG38541.1; EAW80753.1; AAH05198.1; AAH10359.1 

Protein Name

 JNK1/MAPK8-associated membrane protein 

Protein Synonyms/Alias

 JKAMP; JNK1-associated membrane protein; JAMP; Medulloblastoma antigen MU-MB-50.4 

Gene Name

 JKAMP 

Gene Synonyms/Alias

 C14orf100; JAMP; CDA06; HSPC213; HSPC327 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
10	CLGLYCGKTLLFKNG	ubiquitination	[1, 2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity). 

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Ubl conjugation; Unfolded protein response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 326 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
 GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW. 

Interpro

 IPR008485; DUF766. 

Pfam

 PF05571; DUF766 

SMART

  

PROSITE

  

PRINTS