CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038709
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ataxin-2 
Protein Synonyms/Alias
  
Gene Name
 Atxn2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
424IESSAQYKARVALENubiquitination[1]
790SMDQLLSKNREGEKSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1286 AA 
Protein Sequence
MRSSTAAAQR PAAGDPEPRR PAGWAARRSL PRTARRGGRG GAVAYPSAGP PPRGPGAPPR 60
GPRSPPCASD CFGSNGHGAS RPGSRRLLGV CGPPRPFVVV LLPLAPAATP ARACPPGVRA 120
SPPRSGVSSS ARPAPGCPRP ACEPVYGPLT MSLKPQPQPP APATGRKPGG GLLSSPGAAP 180
ASAAVTSASV VPAPAAPVAS SSAAAGGGRP GLGRGRNSSK GLPQPTISFD GIYANVRMVH 240
ILTSVVGSKC EVQVKNGGIY EGVFKTYSPK CDLVLDAAHE KSTESSSGPK REEIMESVLF 300
KCSDFVVVQF KDTDSSYARR DAFTDSALSA KVNGEHKEKD LEPWDAGELT ASEELELEND 360
VSNGWDPNDM FRYNEENYGV VSTYDSSLSS YTVPLERDNS EEFLKREARA NQLAEEIESS 420
AQYKARVALE NDDRSEEEKY TAVQRNCSDR EGHGPNTRDN KYIPPGQRNR EVLSWGSGRQ 480
SSPRMGQPGP GSMPSRAASH TSDFNPNAGS DQRVVNGGVP WPSPCPSPSS RPPSRYQSGP 540
NSLPPRAATP TRPPSRPPSR PSRPPSHPSA HGSPAPVSTM PKRMSSEGPP RMSPKAQRHP 600
RNHRVSAGRG SMSSGLEFVS HNPPSEAAAP PVARTSPAGG TWSSVVSGVP RLSPKTHRPR 660
SPRQSSIGNS PSGPVLASPQ AGIIPAEAVS MPVPAASPTP ASPASNRALT PSIEAKDSRL 720
QDQRQNSPAG SKENVKASET SPSFSKADNK GMSPVVSEHR KQIDDLKKFK NDFRLQPSST 780
SESMDQLLSK NREGEKSRDL IKDKTEASAK DSFIDSSSSS SNCTSGSSKT NSPSISPSML 840
SNAEHKRGPE VTSQGVQTSS PACKQEKDDR EEKKDTTEQV RKSTLNPNAK EFNPRSFSQP 900
KPSTTPTSPR PQAQPSPSMV GHQQPAPVYT QPVCFAPNMM YPVPVSPGVQ PLYPIPMTPM 960
PVNQAKTYRA GKVPNMPQQR QDQHHQSTMM HPASAAGPPI VATPPAYSTQ YVAYSPQQFP 1020
NQPLVQHVPH YQSQHPHVYS PVIQGNARMM APPAHAQPGL VSSSAAQFGA HEQTHAMYAC 1080
PKLPYNKETS PSFYFAISTG SLAQQYAHPN AALHPHTPHP QPSATPTGQQ QSQHGGSHPA 1140
PSPVQHHQHQ AAQALHLASP QQQSAIYHAG LAPTPPSMTP ASNTQSPQSS FPAAQQTVFT 1200
IHPSHVQPAY TTPPHMAHVP QAHVQSGMVP SHPTAHAPMM LMTTQPPGGP QAALAQSALQ 1260
PIPVSTTAHF PYMTHPSVQA HHQQQL 1286 
Gene Ontology
 GO:0010494; C:cytoplasmic stress granule; IEA:Compara.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0005844; C:polysome; IEA:Compara.
 GO:0005802; C:trans-Golgi network; IEA:Compara.
 GO:0021702; P:cerebellar Purkinje cell differentiation; IMP:MGI.
 GO:0033962; P:cytoplasmic mRNA processing body assembly; IEA:Compara.
 GO:0048872; P:homeostasis of number of cells; IMP:MGI.
 GO:0040015; P:negative regulation of multicellular organism growth; IMP:MGI.
 GO:0002091; P:negative regulation of receptor internalization; IEA:Compara.
 GO:0050905; P:neuromuscular process; IMP:MGI.
 GO:0048812; P:neuron projection morphogenesis; IMP:MGI.
 GO:0034063; P:stress granule assembly; IEA:Compara. 
Interpro
 IPR009818; Ataxin-2_C.
 IPR010920; LSM_dom.
 IPR009604; LsmAD_domain.
 IPR025852; SM_dom_ATX. 
Pfam
 PF06741; LsmAD
 PF07145; PAM2
 PF14438; SM-ATX 
SMART
  
PROSITE
  
PRINTS