| Tag | Content |
|---|
| CPLM ID | CPLM-009875 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutaredoxin-1 |
Protein Synonyms/Alias | Grx1 |
Gene Name | grxA |
Gene Synonyms/Alias | grx; b0849; JW0833 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 23 | RAKDLAEKLSNERDD | acetylation | [1] | | 45 | IRAEGITKEDLQQKA | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfide bonds in a coupled system with glutathione reductase. |
Sequence Annotation | DOMAIN 1 85 Glutaredoxin.
DISULFID 11 14 Redox-active. |
Keyword | 3D-structure; Complete proteome; Deoxyribonucleotide synthesis; Direct protein sequencing; Disulfide bond; Electron transport; Redox-active center; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 85 AA |
Protein Sequence | MQTVIFGRSG CPYCVRAKDL AEKLSNERDD FQYQYVDIRA EGITKEDLQQ KAGKPVETVP 60
QIFVDQQHIG GYTDFAAWVK ENLDA 85 |
Gene Ontology | GO:0009055; F:electron carrier activity; IEA:InterPro. GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro. GO:0045454; P:cell redox homeostasis; IEA:InterPro. GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:UniProtKB-KW. GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |