CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-dependent permease PDR15 
Protein Synonyms/Alias
  
Gene Name
 PDR15 
Gene Synonyms/Alias
 YDR406W; D9509.24 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
441PTERIISKEFIEKGTubiquitination[1]
857DSATTEKKILDDSSEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 DOMAIN 171 420 ABC transporter 1.
 DOMAIN 884 1127 ABC transporter 2.
 NP_BIND 920 927 ATP (Potential).
 CARBOHYD 558 558 N-linked (GlcNAc...) (Potential).
 CARBOHYD 744 744 N-linked (GlcNAc...) (Potential).  
Keyword
 ATP-binding; Complete proteome; Glycoprotein; Membrane; Nucleotide-binding; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1529 AA 
Protein Sequence
MSSDIRDVEE RNSRSSSSSS SSNSAAQSIG QHPYRGFDSE AAERVHELAR TLTSQSLLYT 60
ANSNNSSSSN HNAHNADSRS VFSTDMEGVN PVFTNPDTPG YNPKLDPNSD QFSSTAWVQN 120
MANICTSDPD FYKPYSLGCV WKNLSASGDS ADVSYQSTFA NIVPKLLTKG LRLLKPSKEE 180
DTFQILKPMD GCLNPGELLV VLGRPGSGCT TLLKSISSNS HGFKIAKDSI VSYNGLSSSD 240
IRKHYRGEVV YNAESDIHLP HLTVYQTLFT VARMKTPQNR IKGVDREAYA NHVTEVAMAT 300
YGLSHTRDTK VGNDLVRGVS GGERKRVSIA EVAICGARFQ CWDNATRGLD SATALEFIRA 360
LKTQADIGKT AATVAIYQCS QDAYDLFDKV CVLDDGYQLY FGPAKDAKKY FQDMGYYCPP 420
RQTTADFLTS ITSPTERIIS KEFIEKGTRV PQTPKDMAEY WLQSESYKNL IKDIDSTLEK 480
NTDEARNIIR DAHHAKQAKR APPSSPYVVN YGMQVKYLLI RNFWRMKQSA SVTLWQVIGN 540
SVMAFILGSM FYKVMKKNDT STFYFRGAAM FFAILFNAFS CLLEIFSLYE TRPITEKHRT 600
YSLYHPSADA FASVLSEMPP KLITAVCFNI IFYFLVDFRR NGGVFFFYFL INVIATFTLS 660
HLFRCVGSLT KTLQEAMVPA SMLLLAISMY TGFAIPKTKI LGWSIWIWYI NPLAYLFESL 720
MINEFHDRRF PCAQYIPAGP AYQNITGTQR VCSAVGAYPG NDYVLGDDFL KESYDYEHKH 780
KWRGFGIGMA YVVFFFFVYL ILCEYNEGAK QKGEMVVFLR SKIKQLKKEG KLQEKHRPGD 840
IENNAGSSPD SATTEKKILD DSSEGSDSSS DNAGLGLSKS EAIFHWRDLC YDVPIKGGQR 900
RILNNVDGWV KPGTLTALMG ASGAGKTTLL DCLAERVTMG VITGNIFVDG RLRDESFPRS 960
IGYCQQQDLH LKTATVRESL RFSAYLRQPS SVSIEEKNRY VEEVIKILEM QQYSDAVVGV 1020
AGEGLNVEQR KRLTIGVELA ARPKLLVFLD EPTSGLDSQT AWDTCQLMRK LATHGQAILC 1080
TIHQPSAILM QQFDRLLFLQ KGGQTVYFGD LGEGCKTMID YFESKGAHKC PPDANPAEWM 1140
LEVVGAAPGS HATQDYNEVW RNSDEYKAVQ EELDWMEKNL PGRSKEPTAE EHKPFAASLY 1200
YQFKMVTIRL FQQYWRSPDY LWSKFILTIF NQVFIGFTFF KADRSLQGLQ NQMLSIFMYT 1260
VIFNPILQQY LPSFVQQRDL YEARERPSRT FSWLAFFLSQ IIVEIPWNIL AGTIAYCIYY 1320
YAVGFYANAS AAGQLHERGA LFWLFSIAFY VYIGSMGLLM ISFNEVAETA AHMGTLLFTM 1380
ALSFCGVMAT PKVMPRFWIF MYRVSPLTYM IDALLALGVA NVDVKCSNYE MVKFTPPSGT 1440
TCGDYMASYI KLAGTGYLSD PSATDICSFC AVSTTNAFLA TFSSHYYRRW RNYGIFICYI 1500
AFDYIAATFL YWLSRVPKKN GKISEKPKK 1529 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:SGD.
 GO:0042493; P:response to drug; IMP:SGD. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR013525; ABC_2_trans.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase.
 IPR010929; PDR_CDR_ABC.
 IPR005285; Pleiotrop_drug-R_PDR. 
Pfam
 PF01061; ABC2_membrane
 PF00005; ABC_tran
 PF06422; PDR_CDR 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS