| Tag | Content |
|---|
| CPLM ID | CPLM-021111 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Chondroitin sulfate proteoglycan 5 |
Protein Synonyms/Alias | Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C |
Gene Name | Cspg5 |
Gene Synonyms/Alias | Caleb; Ngc |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 532 | HKIQEALKSRLKEEE | ubiquitination | [1] | | 536 | EALKSRLKEEESFNI | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. |
Sequence Annotation | DOMAIN 376 418 EGF-like.
REGION 270 306 Interaction with TNC and TNR (By
REGION 447 465 Interaction with GOPC (By similarity).
CARBOHYD 57 57 N-linked (GlcNAc...) (Potential).
CARBOHYD 76 76 O-linked (GalNAc...) (Potential).
CARBOHYD 123 123 O-linked (Xyl...) (chondroitin sulfate)
CARBOHYD 132 132 O-linked (GalNAc...) (Potential).
CARBOHYD 143 143 O-linked (GalNAc...) (Potential).
CARBOHYD 144 144 O-linked (GalNAc...) (Potential).
CARBOHYD 153 153 O-linked (GalNAc...) (Potential).
CARBOHYD 156 156 O-linked (GalNAc...) (Potential).
CARBOHYD 160 160 O-linked (GalNAc...) (Potential).
CARBOHYD 162 162 O-linked (GalNAc...) (Potential).
CARBOHYD 198 198 O-linked (GalNAc...) (Potential).
CARBOHYD 240 240 O-linked (GalNAc...) (Potential).
CARBOHYD 318 318 O-linked (GalNAc...) (Potential).
CARBOHYD 322 322 O-linked (GalNAc...) (Potential).
CARBOHYD 372 372 N-linked (GlcNAc...) (Potential).
DISULFID 379 392 By similarity.
DISULFID 386 402 By similarity.
DISULFID 404 417 By similarity. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Developmental protein; Differentiation; Direct protein sequencing; Disulfide bond; EGF-like domain; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Growth regulation; Membrane; Neurogenesis; Phosphoprotein; Proteoglycan; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 571 AA |
Protein Sequence | MGRAGGGGPG WGPPPVLLLL GVTLVLTAGA VPAREAGSAI EAEELVRSGL AWESRANDTR 60
EEAGLPAAGE DETSWTERGS ELAAVGPGVG PEETLEASAA VTGTAWLEAD GTGLGGVTAE 120
AGSGDAQTLP ATLQAPDEAL GSSTMPPAIP EATEASGPPS PTLRDKPSLV PELPKEIPLE 180
VWLNLGGSTP DPQRPEPTFP LQGTLETQPA SDIIDIDYFE GLDSEGRGTD MGRFPGSPGT 240
SENHPDTEGE TPSWSLLDLY DDFTPFDESD FYPTTSFYDD LEEEEEEEED KDAVGGGDLE 300
DESDLLLPSQ KPGVGPGTGQ PTSRWHAVPP QHTLGMVPGG SISLRPRPGD PGKDLATSEN 360
GTECRVGFVR HNGSCRSVCD LFPSYCHNGG QCYLVENIGA FCRCNTQDYI WHKGMRCESI 420
ITDFQVMCVA VGSAALVLLL LFMMTVFFAK KLYLLKTENT KLRRTNKFRT PSELHNDNFS 480
LSTIAEGSHP NVRKLCDTPC VSSPHARALA HCDNIVCQDD PSAPHKIQEA LKSRLKEEES 540
FNIQNSMSPK LEGGKGDQDD LEVNCLQNNL T 571 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0031103; P:axon regeneration; IEP:RGD. GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. GO:0050804; P:regulation of synaptic transmission; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |