CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038809
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Nidogen-1 
Protein Synonyms/Alias
  
Gene Name
 Nid1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
436SPQRVNGKVKGRIFVacetylation[1]
529TFLGHPGKLILKQQFacetylation[1]
969TMKKTEAKAFLHIPAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; EGF-like domain; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1246 AA 
Protein Sequence
MLDASGWSWE MWTWALLQLL LLAGPAGCLS RQELFPFGPG QGDLELEAGD DVVSPSLELI 60
GELSFYDRSD ITSVYVTTNG IIAMSEPPAT EFHPGTFPPS FGSVAPFLAD LDTTDGLGNV 120
YYREDLSPFI IQMAAEYVQR GFPEVSFQPT SVVVVTWESM APYGGPSGSL VEEGKRNTFQ 180
AVLASSNSSS YAIFLYPDDG LQFFTTFSKK DENQVPAVVG FSKGLEGFLW KSNGAYNIFA 240
NDRESIENLA KSSNAGHQGV WVFEIGSPAT AKGVVPADVN LDVDDDGADY EDEDYDLQTS 300
HLGLEDVATQ PFPSHSPRRG YPDPHNVPRT LAPSYEATER PHGIPTERTK SFQLPVERFP 360
QKHPQVIDVD EVEETGVVFS YNTGSQQTCA NNRHQCSVHA ECRDYATGFC CRCVANYTGN 420
GRQCVAEGSP QRVNGKVKGR IFVGNSQVPV VFENTDLHSY VVMNHGRSYT AISTIPESVG 480
YSLLPLAPIG GIIGWMFAVE QDGFKNGFSI TGGEFTRQAE VTFLGHPGKL ILKQQFSGID 540
EHGHLTINTE LEGRVPQIPY GASVHIEPYT ELYHYSSSVI TSSSTREYTV TEPDQDSAVP 600
SHTHVYQWRQ TITFQECAHD DSRPALPSTQ QLSVDSVFVL YNKEERILRY ALSNSIGPVR 660
DGSPDALQNP CYIGTHGCDS NAACRPGPGT QFTCECSVGF RGDGKACYDI DECSEQPSRC 720
GNHAICNNHP GTFRCECMEG YHFSDRGICV AAVDQRPINY CETGLHNCDI PQRAQCIYMG 780
GSSYTCSCLP GFSGDGRACQ DVDECQHSRC HPDAFCYNTP GSFRCQCKPG YQGDGFRCVP 840
GEVGKTRCQL EREHILGAAG ATDAQRPTLQ GMFVPQCDEY GHYTPTQCHH STGYCWCVDR 900
DGQELEDTRT PPGMRPPCLS TVAPPIHQGP VVPTAVIPLP PGTHLLFAQT GKIERLPLER 960
NTMKKTEAKA FLHIPAKVII GLAFDCVDKV VYWTDISEPS IGRASLHGGE PTTIIRQDLG 1020
SPEGIALDHL GRTIFWTDSH LDRIEVAKMD GTQRRVLFDT GLVNPRGIVT DSVRGNLYWT 1080
DWNRDNPKIE TSHMDGTNRR ILAQDNLGLP NGLTFDAFSS QLCWVDAGTH RAECLNPAQP 1140
SRRKVLEGLQ YPFAVTSYGK NLYYTDWKTN SVIAMDLAVS KEMDAFHPHK HTRLYGITIA 1200
LSQCPQGHNY CSVNNGGCTH LCLPTPGSRT CRCPDNTLGV DCIERK 1246 
Gene Ontology
 GO:0005605; C:basal lamina; IEA:Compara.
 GO:0071944; C:cell periphery; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0050840; F:extracellular matrix binding; IEA:Compara.
 GO:0007160; P:cell-matrix adhesion; IEA:Compara.
 GO:0032836; P:glomerular basement membrane development; IEA:Compara.
 GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Compara. 
Interpro
 IPR011042; 6-blade_b-propeller_TolB-like.
 IPR026823; cEGF.
 IPR000742; EG-like_dom.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR018097; EGF_Ca-bd_CS.
 IPR024731; EGF_dom_MSP1-like.
 IPR006605; G2_nidogen/fibulin_G2F.
 IPR009017; GFP.
 IPR023413; GFP_like.
 IPR000033; LDLR_classB_rpt.
 IPR003886; Nidogen_extracell_dom.
 IPR000716; Thyroglobulin_1. 
Pfam
 PF12662; cEGF
 PF12947; EGF_3
 PF07645; EGF_CA
 PF07474; G2F
 PF00058; Ldl_recept_b
 PF06119; NIDO
 PF00086; Thyroglobulin_1 
SMART
 SM00181; EGF
 SM00179; EGF_CA
 SM00682; G2F
 SM00135; LY
 SM00539; NIDO
 SM00211; TY 
PROSITE
 PS00010; ASX_HYDROXYL
 PS00022; EGF_1
 PS01186; EGF_2
 PS50026; EGF_3
 PS01187; EGF_CA
 PS51120; LDLRB
 PS51220; NIDO
 PS50993; NIDOGEN_G2
 PS00484; THYROGLOBULIN_1_1
 PS51162; THYROGLOBULIN_1_2 
PRINTS