CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043748
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Diacylglycerol kinase delta 
Protein Synonyms/Alias
  
Gene Name
 DGKD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
115SVMAYEAKLPRQASSubiquitination[1]
185RVGKAYEKTTESSEEubiquitination[1]
379GLPALNTKILYPNVRubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 451 AA 
Protein Sequence
XRFKQLLNPA QVFDLMNGGP HLGLRLFQKF DTFRILVCGG DGSVGWVLSE IDSLNLHKQC 60
QLGVLPLGTG NDLARVLGWG SACDDDTQLP QILEKLERAS TKMLDRWSVM AYEAKLPRQA 120
SSSTVTEDFS EDSEVQQILF YEDSVAAHLS KILTSDQHSV VISSAKVLCE TVKDFVARVG 180
KAYEKTTESS EESEVMAKKC SVLKEKLDSL LKTLDDESQA SSSLPNPPPT IAEEAEDGDG 240
SGSICGSTGD RLVASACPAR PQIFRPREQL MLRANSLKKA IRQIIEHTEK AVDEQNAQTQ 300
EQEGFVLGLS ESEEKMDHRV CPPLSHSESF GVPKGRSQRK VSKSPCEKLI SKGSLSLGSS 360
ASLPPQPGSR DGLPALNTKI LYPNVRAGMS GSLPGGSVIS RLLINADPFN SEPETLERSQ 420
TQSPRPHDPI PVNCLEEAPP WRWKVDERRQ G 451 
Gene Ontology
 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR001206; Diacylglycerol_kinase_cat_dom. 
Pfam
 PF00781; DAGK_cat 
SMART
 SM00046; DAGKc 
PROSITE
 PS50146; DAGK 
PRINTS