CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007417
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein MKT1 
Protein Synonyms/Alias
  
Gene Name
 MKT1 
Gene Synonyms/Alias
 YNL085W; N2302 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
4****MAIKSLESFLFubiquitination[1]
329LRYMPVLKDTGKVELubiquitination[2]
357KNNKDGKKSNLSSPSubiquitination[2]
383VTKNASEKLTYEKSSubiquitination[2]
466SVEIFKNKEINLLTQubiquitination[2]
488IKQIKQVKWYAANEPubiquitination[2]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for propagation of M2 dsRNA satellite at temperature above 30 degrees Celsius if an L-A RNA virus carrying NEX (N) is present in the cells. 
Sequence Annotation
 MOD_RES 358 358 Phosphoserine.
 MOD_RES 362 362 Phosphoserine.
 MOD_RES 371 371 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 830 AA 
Protein Sequence
MAIKSLESFL FERGLVGSYA IEALNNCTLD IDVNHYVSRL LTNKREQYLD AIGGFPTSLK 60
MYLESDLKIF KDFNITPIFV FNGGLTYNQL EASGHFTAAS ASASISSTTT SSSGTNATTR 120
SNTESVLLQR SRGWTQWNNL ISSNQNSYID QPIQPQEPFR HNTTIDSKAY QNDLIAYFIE 180
HGYMYQVAPY SSWFQLAYLL NSAYIDAIYG PTDCLMLDCV DRFILGMEFP NKEFRFIDRS 240
RVMKDLGCTH EEFIDIAMAV GNDLQPTTLP PLQIYPVPQL FDIALEMVLN TGTNFYAYQL 300
STTLQNDSKE NIQNYQRGIS ALRYMPVLKD TGKVELFVQE IVVSEEDSEK NNKDGKKSNL 360
SSPSSASSSA SPATTVTKNA SEKLTYEKSS TKEVRKPRDI PNDVHDFIGQ MLPHEYYFYR 420
SIGLVTGKLF DAIVTGVYPE EPPLGGGSST SYKKLVSKSV EIFKNKEINL LTQPINRYYQ 480
IKQIKQVKWY AANEPTTLTN RMSPSMFETI NHLIVKTETS DEKEFSISEF ITTINGSSNM 540
AKDFISEKVI FPNSVPIESK LNSPFNLLST NFLRLLVLLE FFTFDFKEKL LEPTRWGEVF 600
LKLNELNIDS KYHESVIIFL VFLKCDVLKL DEEVQPPAPS ALSQATLRSY PEESLYVLLI 660
TRVLTLFQVD QKPSNYHGPI DKKTLIFRDH LSFIKENLNE LFEAVLISSL TSGEFNRLSL 720
DNFGWARKIV RYLPFKLDSP NTIMAMMWEF FLQKYLHNGN AKNDALSLVA TEFNTYKSTP 780
NLDEQFVESH RFLLEISKVM QELNAAKLID ENVFKLFTKA VEFTTTALSS 830 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005844; C:polysome; IDA:SGD.
 GO:0004518; F:nuclease activity; ISS:SGD.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0044419; P:interspecies interaction between organisms; IMP:SGD.
 GO:0006974; P:response to DNA damage stimulus; IMP:SGD. 
Interpro
 IPR022039; MKT1_C.
 IPR022040; MKT1_N.
 IPR006086; XPG-I_dom.
 IPR006085; XPG_DNA_repair_N. 
Pfam
 PF12246; MKT1_C
 PF12247; MKT1_N
 PF00867; XPG_I
 PF00752; XPG_N 
SMART
 SM00484; XPGI
 SM00485; XPGN 
PROSITE
  
PRINTS