CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013459
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pyrroline-5-carboxylate reductase 3 
Protein Synonyms/Alias
 P5C reductase 3; P5CR 3; Pyrroline-5-carboxylate reductase-like protein 
Gene Name
 PYCRL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32QGLIRAGKVEAQHILubiquitination[1]
218QTLLGTAKMLLHEGQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Amino-acid biosynthesis; Complete proteome; NADP; Oxidoreductase; Polymorphism; Proline biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 274 AA 
Protein Sequence
MAAAEPSPRR VGFVGAGRMA GAIAQGLIRA GKVEAQHILA SAPTDRNLCH FQALGCRTTH 60
SNQEVLQSCL LVIFATKPHV LPAVLAEVAP VVTTEHILVS VAAGVSLSTL EELLPPNTRV 120
LRVLPNLPCV VQEGAIVMAR GRHVGSSETN LLQHLLEACG RCEEVPEAYV DIHTGLSGSG 180
VAFVCAFSEA LAEGAVKMGM PSSLAHRIAA QTLLGTAKML LHEGQHPAQL RSDVCTPGGT 240
TIYGLHALEQ GGLRAATMSA VEAATCRAKE LSRK 274 
Gene Ontology
 GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:EC.
 GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR016040; NAD(P)-bd_dom.
 IPR004455; NADP_OxRdtase_F420.
 IPR000304; Pyrroline-COOH_reductase. 
Pfam
 PF03807; F420_oxidored 
SMART
  
PROSITE
 PS00521; P5CR 
PRINTS