CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Tetraspanin-14 
Protein Synonyms/Alias
  
Gene Name
 TSPAN14 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52GVLSDLTKVTRMHGIubiquitination[1]
208ISDIEAVKAGHHF**ubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 213 AA 
Protein Sequence
MHYYRYSNAK VSCWYKYLLF SYNIIFWLAG VVFLGVGLWA WSEKGVLSDL TKVTRMHGID 60
PVVLVLMVGV VMFTLGFAGC VGALRENICL LNFNQCCGAY GPEDWDLNVY FNCSGASYSR 120
EKCGVPFSCC VPDPAQKVVN TQCGYDVRIQ LKSKWDESIF TKGCIQALES WLPRNIYIVA 180
GVFIAISLLQ IFGIFLARTL ISDIEAVKAG HHF 213 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00335; Tetraspannin 
SMART
  
PROSITE
 PS00421; TM4_1 
PRINTS
 PR00259; TMFOUR.