CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019001
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable palmitoyltransferase ZDHHC16 
Protein Synonyms/Alias
 Zinc finger DHHC domain-containing protein 16; DHHC-16 
Gene Name
 ZDHHC16 
Gene Synonyms/Alias
 UNQ2570/PRO6258 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
94ATVSICKKCIYPKPAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in apoptosis regulation (By similarity). 
Sequence Annotation
 ZN_FING 155 205 DHHC-type.  
Keyword
 Acyltransferase; Alternative splicing; Apoptosis; Complete proteome; Endoplasmic reticulum; Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 377 AA 
Protein Sequence
MRGQRSLLLG PARLCLRLLL LLGYRRRCPP LLRGLVQRWR YGKVCLRSLL YNSFGGSDTA 60
VDAAFEPVYW LVDNVIRWFG VGRNDIATVS ICKKCIYPKP ARTHHCSICN RCVLKMDHHC 120
PWLNNCVGHY NHRYFFSFCF FMTLGCVYCS YGSWDLFREA YAAIETYHQT PPPTFSFRER 180
MTHKSLVYLW FLCSSVALAL GALTVWHAVL ISRGETSIER HINKKERRRL QAKGRVFRNP 240
YNYGCLDNWK VFLGVDTGRH WLTRVLLPSS HLPHGNGMSW EPPPWVTAHS ASVMAV 296 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 
Interpro
 IPR001594; Znf_DHHC_palmitoyltrfase. 
Pfam
 PF01529; zf-DHHC 
SMART
  
PROSITE
 PS50216; ZF_DHHC 
PRINTS