CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020890
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sulfotransferase 1C2 
Protein Synonyms/Alias
 ST1C2 
Gene Name
 Sult1c2 
Gene Synonyms/Alias
 Sult1c1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
232VLETSFEKMKENPMTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters (By similarity). 
Sequence Annotation
 NP_BIND 49 54 PAPS (By similarity).
 NP_BIND 228 233 PAPS (By similarity).
 NP_BIND 256 260 PAPS (By similarity).
 REGION 107 109 Substrate binding (By similarity).
 ACT_SITE 109 109 Proton acceptor (By similarity).
 BINDING 131 131 PAPS (By similarity).
 BINDING 139 139 PAPS (By similarity).
 BINDING 194 194 PAPS (By similarity).  
Keyword
 Complete proteome; Lysosome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 296 AA 
Protein Sequence
MALTPELSRQ TKLKEVAGIP LQAPTVDNWR QIQTFEAKPD DLLICTYPKS GTTWIQEIVD 60
MIEQNGDVEK CRRTIIQHRH PFIEWARPPQ PSGVDKANEM PAPRILRTHL PTQLLPPSFW 120
TNNCKFLYVA RNAKDCMVSY YHFYRMSQVL PEPGTWDEYF ETFINGKVSW GSWFDHVKGW 180
WEIRDKYQIL FLFYEDMKRN PKHEIQKVMQ FMGKNLDEDV VDKIVLETSF EKMKENPMTN 240
RSTAPKSILD QSISPFMRKG TVGDWKNHFT VAQNERFDEI YKQKMGRTSL NFSMEL 296 
Gene Ontology
 GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
 GO:0015630; C:microtubule cytoskeleton; IEA:Compara.
 GO:0008146; F:sulfotransferase activity; IEA:Compara.
 GO:0051923; P:sulfation; IEA:Compara. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR000863; Sulfotransferase_dom. 
Pfam
 PF00685; Sulfotransfer_1 
SMART
  
PROSITE
  
PRINTS