CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021426
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HAUS augmin-like complex subunit 4 
Protein Synonyms/Alias
  
Gene Name
 HAUS4 
Gene Synonyms/Alias
 C14orf94 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
110NVTSEDKKDFVWMRAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. 
Sequence Annotation
  
Keyword
 Alternative splicing; Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitosis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 363 AA 
Protein Sequence
MASGDFCSPG EGMEILQQVC SKQLPPCNLS KEDLLQNPYF SKLLLNLSQH VDESGLSLTL 60
AKEQAQAWKE VRLHKTTWLR SEILHRVIQE LLVDYYVKIQ DTNVTSEDKK DFVWMRARLQ 120
QEVEEQLKKK CFTLLCYYDP NSDADSETVK AAKVWKLAEV LVGEQQQCQD AKSQQKEQML 180
LLEKKSAAYS QVLLRCLTLL QRLLQEHRLK TQSELDRINA QYLEVKCGAM ILKLRMEELK 240
ILSDTYTVEK VEVHRLIRDR LEGAIHLQEQ DMENSRQVLN SYEVLGEEFD RLVKEYTVLK 300
QATENKRWAL QEFSKVYR 318 
Gene Ontology
 GO:0005813; C:centrosome; IDA:UniProtKB.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0070652; C:HAUS complex; IDA:UniProtKB.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0051297; P:centrosome organization; IMP:UniProtKB.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0051225; P:spindle assembly; IMP:UniProtKB. 
Interpro
 IPR026214; HAUS4. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR02090; HAUSAUGMINL4.