UniProt Accession

 NACA_DROME; Q94518; A4UZF1; O16813; Q0E999 

Genbank Protein ID

 Y08969; AF017783; AE013599; AE013599; AY075332 

Genbank Nucleotide ID

 CAA70166.1; AAB97513.1; AAM68653.1; AAM68654.1; AAL68199.1 

Protein Name

 Nascent polypeptide-associated complex subunit alpha 

Protein Synonyms/Alias

 NAC-alpha; Alpha-NAC 

Gene Name

 Nacalpha 

Gene Synonyms/Alias

 aic; CG8759 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
142	AQVAAAEKFKAPEAA	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 May promote appropriate targeting of ribosome-nascent polypeptide complexes (By similarity). Required for correct localization of the osk/oskar protein to the posterior pole during embryonic development. The osk protein directs the recruitment of molecules responsible for posterior body patterning and germline formation in the embryo. 

Sequence Annotation

 DOMAIN 70 135 NAC-A/B.
 DOMAIN 177 217 UBA.  

Keyword

 Complete proteome; Developmental protein; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0048477; P:oogenesis; IMP:FlyBase.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 

Interpro

 IPR016641; EGD2/NACA.
 IPR002715; Nas_poly-pep-assoc_cplx_dom. 

Pfam

 PF01849; NAC 

SMART

  

PROSITE

 PS51151; NAC_AB
 PS50030; UBA 

PRINTS