CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027014
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Aspartyl-tRNA synthetase 
Protein Synonyms/Alias
 GM14334p 
Gene Name
 Aats-asp 
Gene Synonyms/Alias
 CG3821; Dmel_CG3821 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
413LGRLVKAKYDTDFYIacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 531 AA 
Protein Sequence
MVEDKEQVAN GEQVSKKGAK KLAKAAKKAE QKAENASTAA ANNAGGDSAE DHAAGRYGLS 60
EMIQSKDKRS ERNFVPVSEL SGQVGKGLVW VRGRVHTSRA KGKQCFLILR QQSSTVQCIL 120
AVGDVISKQM VKFAGNIPKE SIIDIQAKPV AVSSKIESCT EQSLELSVEQ IFVISQAKAQ 180
LPLQIEDASR PENADDAEGL NIRVNQDTRL DNRVLDLRTP ANQAIFRLEA GVCRLFRDIL 240
TEQGFTEIHT PKIISAASEG GANVFTVSYF KDSAYLAQSP QLYKQMAIAA DFDKVYTVGA 300
VFRAEDSNTH RHLTEFVGLD LEMAFKYHYH EVLHTIGNTF TSIFKGLRDK YAKEIESVGQ 360
QYKVDAFKFL EPPLILQFAD GVAMLREAGV ETGDEEDLST PNEKLLGRLV KAKYDTDFYI 420
LDKFPLAIRP FYTMPDPNNP VYSNSYDMFM RGEEILSGAQ RIHDPEYLIE RAKHHGIDTS 480
KIAAYIESFR YGCPPHAGGG IGMERVVMLY LGLDNIRKTS MFPRDPKRLT P 531 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0004815; F:aspartate-tRNA ligase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0006422; P:aspartyl-tRNA aminoacylation; IEA:InterPro.
 GO:0040007; P:growth; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase. 
Interpro
 IPR004364; aa-tRNA-synt_II.
 IPR018150; aa-tRNA-synt_II-like.
 IPR006195; aa-tRNA-synth_II.
 IPR004523; Asp-tRNA_synthase.
 IPR002312; Asp/Asn-tRNA-synth_IIb.
 IPR012340; NA-bd_OB-fold.
 IPR004365; NA-bd_OB_tRNA-helicase. 
Pfam
 PF00152; tRNA-synt_2
 PF01336; tRNA_anti 
SMART
  
PROSITE
 PS50862; AA_TRNA_LIGASE_II 
PRINTS
 PR01042; TRNASYNTHASP.