| Tag | Content |
|---|
| CPLM ID | CPLM-006671 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphoglucomutase-1 |
Protein Synonyms/Alias | PGM 1; Glucose phosphomutase 1 |
Gene Name | PGM1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 164 | APEAITDKIFQISKT | ubiquitination | [1] | | 367 | DRVASATKIALYETP | ubiquitination | [1] | | 437 | ILKDHWQKYGRNFFT | ubiquitination | [1] |
|
Reference | [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties. Chen Z, Zhou Y, Song J, Zhang Z. Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [ PMID: 23603789] |
Functional Description | This enzyme participates in both the breakdown and synthesis of glucose. |
Sequence Annotation | ACT_SITE 117 117 Phosphoserine intermediate (By
METAL 117 117 Magnesium; via phosphate group (By
METAL 288 288 Magnesium (By similarity).
METAL 290 290 Magnesium (By similarity).
METAL 292 292 Magnesium (By similarity).
MOD_RES 16 16 N6-acetyllysine.
MOD_RES 115 115 Phosphothreonine (By similarity).
MOD_RES 117 117 Phosphoserine.
MOD_RES 353 353 Phosphotyrosine (By similarity).
MOD_RES 467 467 Phosphothreonine; by PAK1. |
Keyword | Acetylation; Alternative splicing; Carbohydrate metabolism; Complete proteome; Congenital disorder of glycosylation; Cytoplasm; Disease mutation; Glucose metabolism; Glycogen storage disease; Isomerase; Magnesium; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 562 AA |
Protein Sequence | MSDFEEWISG TYRKMEEGPL PLLTFATAPY HDQKPGTSGL RKKTYYFEEK PCYLENFIQS 60
IFFSIDLKDR QGSSLVVGGD GRYFNKSAIE TIVQMAAANG IGRLVIGQNG ILSTPAVSCI 120
IRKIKAIGGI ILTASHNPGG PNGDFGIKFN ISNGGPAPEA ITDKIFQISK TIEEYAVCPD 180
LKVDLGVLGK QQFDLENKFK PFTVEIVDSV EAYATMLRSI FDFSALKELL SGPNRLKIRI 240
DAMHGVVGPY VKKILCEELG APANSAVNCV PLEDFGGHHP DPNLTYAADL VETMKSGEHD 300
FGAAFDGDGD RNMILGKHGF FVNPSDSVAV IAANIFSIPY FQQTGVRGFA RSMPTSGALD 360
RVASATKIAL YETPTGWKFF GNLMDASKLS LCGEESFGTG SDHIREKDGL WAVLAWLSIL 420
ATRKQSVEDI LKDHWQKYGR NFFTRYDYEE VEAEGANKMM KDLEALMFDR SFVGKQFSAN 480
DKVYTVEKAD NFEYSDPVDG SISRNQGLRL IFTDGSRIVF RLSGTGSAGA TIRLYIDSYE 540
KDVAKINQDP QVMLAPLISI ALKVSQLQER TGRTAPTVIT 580 |
Gene Ontology | GO:0015629; C:actin cytoskeleton; IDA:HPA. GO:0005829; C:cytosol; IBA:RefGenome. GO:0000287; F:magnesium ion binding; IEA:InterPro. GO:0004614; F:phosphoglucomutase activity; IDA:UniProtKB. GO:0019388; P:galactose catabolic process; IBA:RefGenome. GO:0006094; P:gluconeogenesis; TAS:UniProtKB. GO:0005978; P:glycogen biosynthetic process; IBA:RefGenome. GO:0005980; P:glycogen catabolic process; TAS:Reactome. GO:0006096; P:glycolysis; TAS:UniProtKB. GO:0044281; P:small molecule metabolic process; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |