CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028912
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 V-crk sarcoma virus CT10 oncogene homolog (Avian)-like 
Protein Synonyms/Alias
  
Gene Name
 Crkl 
Gene Synonyms/Alias
 mCG_131167 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
180IPVPYVEKLVRSSPHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 303 AA 
Protein Sequence
MSSARFDSSD RSAWYMGPVT RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH 60
YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPV GSVSAPNLPT 120
AEENLEYVRT LYDFPGNDAE DLPFKKGELL VIIEKPEEQW WSARNKDGRV GMIPVPYVEK 180
LVRSSPHGKH GNRNSNSYGI PEPAHAYAQP QTTTPLPTVA STPGAAINPL PSTQNGPVFA 240
KAIQKRVPCA YDKTALALEV GDIVKVTRMN INGQWEGEVN GRKGLFPFTH VKIFDPQNPD 300
DNE 303 
Gene Ontology
 GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.
 GO:0001568; P:blood vessel development; IGI:MGI.
 GO:0007507; P:heart development; IGI:MGI.
 GO:0009887; P:organ morphogenesis; IMP:MGI.
 GO:0060017; P:parathyroid gland development; IGI:MGI.
 GO:0048538; P:thymus development; IGI:MGI. 
Interpro
 IPR000980; SH2.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00017; SH2
 PF00018; SH3_1
 PF07653; SH3_2 
SMART
 SM00252; SH2
 SM00326; SH3 
PROSITE
 PS50001; SH2
 PS50002; SH3 
PRINTS
 PR00401; SH2DOMAIN.
 PR00452; SH3DOMAIN.