CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038549
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mediator of RNA polymerase II transcription subunit 15 
Protein Synonyms/Alias
  
Gene Name
 Med15 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
18RSAAFRQKLVSQIEDubiquitination[1]
539DILTDPSKRCPLKTLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 749 AA 
Protein Sequence
MDVSGQETDW RSAAFRQKLV SQIEDAMRKA GVAHSKSSKD MESHVFLKAK TRDEYLSLVA 60
RLIIHFRDIH NKKSQASVSD PMNALQSLTG GPTPGAAGIG MPPRGPGQSL GGMGGLGAMG 120
QPLPLSGQPP PGTSGMAPHG MAVVSTATPQ TQLQLQQVAL QQQQQQQQQQ QFQQQQAALQ 180
QQQQQQQQQQ QQQQFQAQQN AMQQQFQAVV QQQQLQQQQQ QQHLIKLHHQ SQQQQIQQQQ 240
LQRMAQLQLQ QQQQQQQQQA LQAQPPMQQP SMQQPQPPPS QALPQQLSQL HHPQHHQPPP 300
QAQQSPIAQN QPPQIPPQSQ SQPLVSQAQA LPGPMLYAAQ QQLKFVRAPM VVQQPQVQPQ 360
VQQVQPQVQP QAAVQAAQSA QMVAPGVQVS QSSLTMLSSP SPGQQVQTPQ SMPPPPQPSP 420
QPGSQPNSNV SSGPAPSPSS FLPSPSPQPS QSPVTARTPQ NFSVPSPGPL NTPVNPSSVM 480
SPAGSSQAEE QQYLDKLKQL SKYIEPLRRM INKIDKNEDR KKDLSKMKSL LDILTDPSKR 540
CPLKTLQKCE IALEKLKNDM AVPTPPPPPV LPTKQQDLCQ PLLDAVLANI RSPVFNHSLY 600
RTFVPAMMAI HGPPIVSPVV CSRKRRFEED ERQSIPNVLQ GEVARLDPKF LVNLDPSHCS 660
NNGTVHLICK LDDKDLPSVP PLELSVPADY PAQSPMWIDR QWQYDANPFL QSVHRCMTSR 720
LLQLPDKHSV TALLNTWAQS IHQACLSAA 749 
Gene Ontology
 GO:0016592; C:mediator complex; IEA:InterPro.
 GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
 GO:0019827; P:stem cell maintenance; IMP:MGI. 
Interpro
 IPR019087; Mediator_Med15_met. 
Pfam
 PF09606; Med15 
SMART
  
PROSITE
  
PRINTS