CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025472
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Cyp46a1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
69DVFLDWAKKYGPVVRubiquitination[1]
255RLLRQVGKDWVQRRRubiquitination[1]
339VDEVVGSKRHLDYEDubiquitination[1]
358QYLSQVLKESLRLYPubiquitination[1]
422RFGPGAPKPRFTYFPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 500 AA 
Protein Sequence
MSPGLLLLGS AVLLAFGLCC TFVHRARSRY EHIPGPPRPS FLLGHLPYFW KKDEDCGRVL 60
QDVFLDWAKK YGPVVRVNVF YKTSVIVTSP ESVKKFLMST KYNKDSKMYR ALQTVFGERL 120
FGQGLVSECD YGRWYKQRKV MDLAFSRSSL VSLMETFNEK AEQLVEILEA KADGQTPVSM 180
QDMLTCATID ILAKAAFGME TSMLLGAQKP LSQAVKVMLE GISASRNTLA KFMPGKRKQL 240
REIRESIRLL RQVGKDWVQR RREALKRGED MPADILTQIL KAEEGAQDDE VLLDNFVTFF 300
IAGHETSANH LAFTVMELSR QPEIVARLQA EVDEVVGSKR HLDYEDLGRL QYLSQVLKES 360
LRLYPPAWGT FRLLEEETLI DGVRVPGNTP LLFSTYVMGR MDTYFEDPLT FNPDRFGPGA 420
PKPRFTYFPF SLGHRSCIGQ QFAQMEVKVV MAKLLQRIEF RLVPGQRFGL QEQATLKPLD 480
PVLCTLRPRG WQPAPPPPPC 500 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR00385; P450.