| Tag | Content |
|---|
| CPLM ID | CPLM-024665 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
Protein Synonyms/Alias | 4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT |
Gene Name | Aasdhppt |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 151 | FFHIMKRKFTNKEWE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'- phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN (By similarity). |
Sequence Annotation | REGION 86 91 Coenzyme A binding (By similarity).
REGION 108 111 Coenzyme A binding (By similarity).
REGION 181 185 Coenzyme A binding (By similarity).
METAL 129 129 Magnesium (By similarity).
METAL 181 181 Magnesium (By similarity).
BINDING 47 47 Coenzyme A (By similarity). |
Keyword | Complete proteome; Cytoplasm; Magnesium; Metal-binding; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 309 AA |
Protein Sequence | MVFPAKRLCV VPYMEGVRWA FSCGTWLPSP AEWLLAVRSI QPEEKERIGQ FVFARDAKAA 60
LAGRLMIRKL VAEKLNIPWD HIRLQRTSKG KPILAKDTLN PYPNFNFNIS HQGDYTVLAA 120
EPELQVGIDI MKTSFPGRGS IPEFFHIMKR KFTNKEWETI RSFNDEWSQL DMFYRHWALK 180
ESFIKAIGVG LGFEMQRLEF DVSPLSMDIG QVYKETRLIL DGEEEKEWAF EESKIDQHHF 240
VAVALRKPDG SRHQNVSYQD DSKPSQRQFT ILNFNDLIAS AIPMTPEDPS FWDCFCFTEE 300
ILIRNGSKS 309 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0008897; F:holo-[acyl-carrier-protein] synthase activity; ISS:UniProtKB. GO:0000287; F:magnesium ion binding; ISS:UniProtKB. GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |