CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002654
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ornithine decarboxylase 
Protein Synonyms/Alias
 ODC 
Gene Name
 SPE1 
Gene Synonyms/Alias
 ORD1; YKL184W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
395AVLDSINKTRSEYPYubiquitination[1]
403TRSEYPYKVSIWGPTubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 ACT_SITE 411 411 Proton donor; shared with dimeric partner
 MOD_RES 116 116 N6-(pyridoxal phosphate)lysine (By  
Keyword
 Complete proteome; Decarboxylase; Lyase; Polyamine biosynthesis; Pyridoxal phosphate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 466 AA 
Protein Sequence
MSSTQVGNAL SSSTTTLVDL SNSTVTQKKQ YYKDGETLHN LLLELKNNQD LELLPHEQAH 60
PKIFQALKAR IGRINNETCD PGEENSFFIC DLGEVKRLFN NWVKELPRIK PFYAVKCNPD 120
TKVLSLLAEL GVNFDCASKV EIDRVLSMNI SPDRIVYANP CKVASFIRYA ASKNVMKSTF 180
DNVEELHKIK KFHPESQLLL RIATDDSTAQ CRLSTKYGCE MENVDVLLKA IKELGLNLAG 240
VSFHVGSGAS DFTSLYKAVR DARTVFDKAA NEYGLPPLKI LDVGGGFQFE SFKESTAVLR 300
LALEEFFPVG CGVDIIAEPG RYFVATAFTL ASHVIAKRKL SENEAMIYTN DGVYGNMNCI 360
LFDHQEPHPR TLYHNLEFHY DDFESTTAVL DSINKTRSEY PYKVSIWGPT CDGLDCIAKE 420
YYMKHDVIVG DWFYFPALGA YTSSAATQFN GFEQTADIVY IDSELD 466 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0004586; F:ornithine decarboxylase activity; IDA:SGD.
 GO:0015940; P:pantothenate biosynthetic process; IMP:SGD.
 GO:0009446; P:putrescine biosynthetic process; IMP:SGD.
 GO:0033387; P:putrescine biosynthetic process from ornithine; IEA:UniProtKB-UniPathway. 
Interpro
 IPR009006; Ala_racemase/Decarboxylase_C.
 IPR022643; De-COase2_C.
 IPR022657; De-COase2_CS.
 IPR022644; De-COase2_N.
 IPR022653; De-COase2_pyr-phos_BS.
 IPR000183; Orn/DAP/Arg_de-COase.
 IPR002433; Orn_de-COase. 
Pfam
 PF02784; Orn_Arg_deC_N
 PF00278; Orn_DAP_Arg_deC 
SMART
  
PROSITE
 PS00878; ODR_DC_2_1
 PS00879; ODR_DC_2_2 
PRINTS
 PR01179; ODADCRBXLASE.
 PR01182; ORNDCRBXLASE.