UniProt Accession

 T126A_HUMAN; Q9H061; B2R570; E9PI16 

Genbank Protein ID

 AL136941; AK312081; AP000642; CH471076; BC007875 

Genbank Nucleotide ID

 CAB66875.1; BAG35017.1; EAW75102.1; AAH07875.1 

Protein Name

 Transmembrane protein 126A 

Protein Synonyms/Alias

  

Gene Name

 TMEM126A 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	TIVDISRKINQLPEA	ubiquitination	[1]
62	RRILNVTKARIAAGL	ubiquitination	[1]
183	EQYKLLIKALQLSEP	ubiquitination	[2, 3]
192	LQLSEPGKEIH****	ubiquitination	[2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Alternative splicing; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 195 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:UniProtKB.
 GO:0021554; P:optic nerve development; IMP:BHF-UCL. 

Interpro

 IPR009801; DUF1370_TMEM126. 

Pfam

 PF07114; DUF1370 

SMART

  

PROSITE

  

PRINTS