| Tag | Content |
|---|
| CPLM ID | CPLM-001841 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anthranilate synthase component 2 |
Protein Synonyms/Alias | Anthranilate synthase component II; Glutamine amidotransferase; Indole-3-glycerol phosphate synthase; PRAI |
Gene Name | TRP3 |
Gene Synonyms/Alias | YKL211C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 129 | HDNCGIFKNVPQGIA | acetylation | [1] | | 287 | SKGPICLKAVAAEQA | acetylation | [1] | | 343 | ERPCVLRKEFIFSKY | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | |
Sequence Annotation | DOMAIN 13 207 Glutamine amidotransferase type-1.
REGION 215 484 Indole-3-glycerol phosphate synthase.
ACT_SITE 92 92 For GATase activity (By similarity).
ACT_SITE 181 181 For GATase activity (By similarity).
ACT_SITE 183 183 For GATase activity (By similarity).
MOD_RES 2 2 Phosphoserine. |
Keyword | Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; Glutamine amidotransferase; Lyase; Multifunctional enzyme; Phosphoprotein; Reference proteome; Transferase; Tryptophan biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 484 AA |
Protein Sequence | MSVHAATNPI NKHVVLIDNY DSFTWNVYEY LCQEGAKVSV YRNDAITVPE IAALNPDTLL 60
ISPGPGHPKT DSGISRDCIR YFTGKIPVFG ICMGQQCMFD VFGGEVAYAG EIVHGKTSPI 120
SHDNCGIFKN VPQGIAVTRY HSLAGTESSL PSCLKVTAST ENGIIMGVRH KKYTVEGVQF 180
HPESILTEEG HLMIRNILNV SGGTWEENKS SPSNSILDRI YARRKIDVNE QSKIPGFTFQ 240
DLQSNYDLGL APPLQDFYTV LSSSHKRAVV LAEVKRASPS KGPICLKAVA AEQALKYAEA 300
GASAISVLTE PHWFHGSLQD LVNVRKILDL KFPPKERPCV LRKEFIFSKY QILEARLAGA 360
DTVLLIVKML SQPLLKELYS YSKDLNMEPL VEVNSKEELQ RALEIGAKVV GVNNRDLHSF 420
NVDLNTTSNL VESIPKDVLL IALSGITTRD DAEKYKKEGV HGFLVGEALM KSTDVKKFIH 480
ELCE 484 |
Gene Ontology | GO:0005950; C:anthranilate synthase complex; IPI:SGD. GO:0004049; F:anthranilate synthase activity; IEA:EC. GO:0004425; F:indole-3-glycerol-phosphate synthase activity; IMP:SGD. GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:InterPro. GO:0016740; F:transferase activity; IEA:UniProtKB-KW. GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. GO:0000162; P:tryptophan biosynthetic process; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |