CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027191
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG13402, isoform CRA_a 
Protein Synonyms/Alias
 Polypyrimidine tract-binding protein 1 
Gene Name
 Ptbp1 
Gene Synonyms/Alias
 mCG_13402 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
372VKILFNKKENALVQMubiquitination[1]
396MSHLNGHKLHGKSVRubiquitination[1]
408SVRITLSKHQSVQLPacetylation[2, 3]
408SVRITLSKHQSVQLPubiquitination[1]
426QEDQGLTKDYGSSPLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 529 AA 
Protein Sequence
MDGIVPDIAV GTKRGSDELF STCVSNGPFI MSSSASAANG NDSKKFKGDN RSAGVPSRVI 60
HVRKLPSDVT EGEVISLGLP FGKVTNLLML KGKNQAFIEM NTEEAANTMV NYYTSVAPVL 120
RGQPIYIQFS NHKELKTDSS PNQARAQAAL QAVNSVQSGN LALAASAAAV DAGMAMAGQS 180
PVLRIIVENL FYPVTLDVLH QIFSKFGTVL KIITFTKNNQ FQALLQYADP VSAQHAKLSL 240
DGQNIYNACC TLRIDFSKLT SLNVKYNNDK SRDYTRPDLP SGDSQPSLDQ TMAAAFGLSV 300
PNVHGALAPL AIPSAAAAAA ASRIAIPGLA GAGNSVLLVS NLNPERVTPQ SLFILFGVYG 360
DVQRVKILFN KKENALVQMA DGSQAQLAMS HLNGHKLHGK SVRITLSKHQ SVQLPREGQE 420
DQGLTKDYGS SPLHRFKKPG SKNFQNIFPP SATLHLSNIP PSVSEDDLKS LFSSNGGVVK 480
GFKFFQKDRK MALIQMGSVE EAVQALIELH NHDLGENHHL RVSFSKSTI 529 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:InterPro. 
Interpro
 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS