CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000243
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein beta-6 
Protein Synonyms/Alias
 HspB6; Heat shock 20 kDa-like protein p20 
Gene Name
 HSPB6 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
160APPPAAAK*******acetylation[1]
Reference
 [1] Acetylation of heat shock protein 20 (Hsp20) regulates human myometrial activity.
 Karolczak-Bayatti M, Sweeney M, Cheng J, Edey L, Robson SC, Ulrich SM, Treumann A, Taggart MJ, Europe-Finner GN.
 J Biol Chem. 2011 Sep 30;286(39):34346-55. [PMID: 21803775
Functional Description
  
Sequence Annotation
 MOD_RES 16 16 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 160 AA 
Protein Sequence
MEIPVPVQPS WLRRASAPLP GLSAPGRLFD QRFGEGLLEA ELAALCPTTL APYYLRAPSV 60
ALPVAQVPTD PGHFSVLLDV KHFSPEEIAV KVVGEHVEVH ARHEERPDEH GFVAREFHRR 120
YRLPPGVDPA AVTSALSPEG VLSIQAAPAS AQAPPPAAAK 160 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
 GO:0005212; F:structural constituent of eye lens; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR002068; a-crystallin/Hsp20_dom.
 IPR001436; Alpha-crystallin/HSP.
 IPR003090; Alpha-crystallin_N.
 IPR008978; HSP20-like_chaperone. 
Pfam
 PF00525; Crystallin
 PF00011; HSP20 
SMART
  
PROSITE
 PS01031; HSP20 
PRINTS
 PR00299; ACRYSTALLIN.