UniProt Accession

 MYP0_RAT; P06907 

Genbank Protein ID

 K03242 

Genbank Nucleotide ID

 AAA41576.1 

Protein Name

 Myelin protein P0 

Protein Synonyms/Alias

 Myelin peripheral protein; MPP; Myelin protein zero 

Gene Name

 Mpz 

Gene Synonyms/Alias

 P0 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
96	IDEVGTFKERIQWVG	acetylation	[1]
199	RRLSAMEKGKFHKSS	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae (By similarity). 

Sequence Annotation

 DOMAIN 30 143 Ig-like V-type.
 MOD_RES 210 210 Phosphoserine; by PKC (By similarity).
 MOD_RES 216 216 Phosphothreonine (By similarity).
 MOD_RES 226 226 Phosphoserine (By similarity).
 MOD_RES 228 228 Phosphoserine (By similarity).
 MOD_RES 233 233 Phosphoserine; by PKC (By similarity).
 MOD_RES 237 237 Phosphoserine (By similarity).
 MOD_RES 243 243 Phosphoserine; by PKC (By similarity).
 CARBOHYD 122 122 N-linked (GlcNAc...) (complex)
 DISULFID 50 127  

Keyword

 3D-structure; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Membrane; Phosphoprotein; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0045217; P:cell-cell junction maintenance; IEA:Compara. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr.
 IPR019566; Myelin-PO_C.
 IPR000920; Myelin_P0.
 IPR019738; Myelin_P0_CS. 

Pfam

 PF10570; Myelin-PO_C
 PF07686; V-set 

SMART

 SM00406; IGv 

PROSITE

 PS50835; IG_LIKE
 PS00568; MYELIN_P0 

PRINTS

 PR00213; MYELINP0.