UniProt Accession

 AT2L1_MOUSE; Q8BWU8; Q811K4; Q9DBB3 

Genbank Protein ID

 AK005060; AK049937; BC043680; BC058592 

Genbank Nucleotide ID

 BAB23784.1; BAC33993.1; AAH43680.2; AAH58592.1 

Protein Name

 Ethanolamine-phosphate phospho-lyase 

Protein Synonyms/Alias

 Alanine--glyoxylate aminotransferase 2-like 1 

Gene Name

 Etnppl 

Gene Synonyms/Alias

 Agxt2l1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
23	RHIGPSCKIFFAADP	acetylation	[1]
32	FFAADPIKIMRAQGQ	ubiquitination	[2]
45	GQYMFDEKGERYLDC	ubiquitination	[2]
72	EVVKAAAKQMELLNT	ubiquitination	[2]
93	DNIIEFAKRLTATLP	ubiquitination	[2]
177	APDTYRGKYREDHED	ubiquitination	[2]
351	MELLSEQKAKHPLIG	ubiquitination	[2]
460	AYRTKMPKEIQVELP	ubiquitination	[2]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde (By similarity). 

Sequence Annotation

 MOD_RES 278 278 N6-(pyridoxal phosphate)lysine (By  

Keyword

 Aminotransferase; Complete proteome; Lyase; Mitochondrion; Pyridoxal phosphate; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 499 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0050459; F:ethanolamine-phosphate phospho-lyase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
 GO:0008152; P:metabolic process; IEA:GOC. 

Interpro

 IPR005814; Aminotrans_3.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 

Pfam

 PF00202; Aminotran_3 

SMART

  

PROSITE

 PS00600; AA_TRANSFER_CLASS_3 

PRINTS