| Tag | Content |
|---|
| CPLM ID | CPLM-020487 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Myosin regulatory light polypeptide 9 |
Protein Synonyms/Alias | Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9 |
Gene Name | Myl9 |
Gene Synonyms/Alias | Myrl2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 150 | YREAPIDKKGNFNYV | ubiquitination | [1] | | 151 | REAPIDKKGNFNYVE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). |
Sequence Annotation | DOMAIN 29 64 EF-hand 1.
DOMAIN 98 133 EF-hand 2.
DOMAIN 134 169 EF-hand 3.
MOD_RES 2 2 N-acetylserine (By similarity).
MOD_RES 19 19 Phosphothreonine; by MLCK, CIT and ROCK2.
MOD_RES 20 20 Phosphoserine; by CDC42BP, CIT, MLCK,
MOD_RES 29 29 Phosphoserine.
MOD_RES 135 135 Phosphothreonine. |
Keyword | Acetylation; Calcium; Complete proteome; Metal-binding; Motor protein; Muscle protein; Myosin; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 172 AA |
Protein Sequence | MSSKRAKAKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS 60
LGKNPTDEYL EGMMNEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEASGFIHE 120
DHLRELLTTM GDRFTDEEVD EMYREAPIDK KGNFNYVEFT RILKHGAKDK DD 172 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |