CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021124
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PRA1 family protein 3 
Protein Synonyms/Alias
 ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5; GTRAP3-18; Glutamate transporter EAAC1-interacting protein; Prenylated Rab acceptor protein 2; Protein JWa 
Gene Name
 Arl6ip5 
Gene Synonyms/Alias
 Gtrap3-18; Jwa; Pra2; Praf3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
185KFADYISKARE****ubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic. 
Sequence Annotation
 REGION 136 188 Targeting to endoplasmic reticulum
 MOD_RES 1 1 N-acetylmethionine (By similarity).  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 188 AA 
Protein Sequence
MDVNLAPLRA WDDFFPGSDR FARPDFRDIS KWNNRVVSNL LYYQTNYLVV AAMMISVVGF 60
LSPFNMILGG IIVVLVFTGF VWAAHNKDIL RRMKKQYPTA FVMVVMLASY FLISMFGGVM 120
VFVFGITFPL LLMFIHASLR LRNLKNKLEN KMEGIGLKKT PMGIILDALE QQEDSINKFA 180
DYISKARE 188 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; IDA:RGD.
 GO:0008022; F:protein C-terminus binding; IDA:RGD.
 GO:0015813; P:L-glutamate transport; IEA:Compara.
 GO:0051051; P:negative regulation of transport; IMP:RGD. 
Interpro
 IPR004895; Prenylated_rab_accept_PRA1. 
Pfam
 PF03208; PRA1 
SMART
  
PROSITE
  
PRINTS