CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016719
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable G-protein coupled receptor 158 
Protein Synonyms/Alias
  
Gene Name
 Gpr158 
Gene Synonyms/Alias
 Kiaa1136 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
720DIRDELKKLYAQLEIubiquitination[1]
732LEIYKRKKMITNNPHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Orphan receptor. 
Sequence Annotation
 MOD_RES 904 904 Phosphoserine.
 MOD_RES 976 976 Phosphoserine.
 CARBOHYD 98 98 N-linked (GlcNAc...) (Potential).
 CARBOHYD 143 143 N-linked (GlcNAc...) (Potential).
 CARBOHYD 215 215 N-linked (GlcNAc...) (Potential).
 CARBOHYD 274 274 N-linked (GlcNAc...) (Potential).
 CARBOHYD 333 333 N-linked (GlcNAc...) (Potential).
 CROSSLNK 774 774 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Cell membrane; Complete proteome; G-protein coupled receptor; Glycoprotein; Isopeptide bond; Membrane; Phosphoprotein; Receptor; Reference proteome; Signal; Transducer; Transmembrane; Transmembrane helix; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1200 AA 
Protein Sequence
MGAMAYSLLF CLLLAHLGLG EVGASLDPPG RPDSPRERTP RGKQHGQQLP RASAPDPSIP 60
WSRSTDGTIL AQKLAEEVPV DVASYLYTGD FHQLKRANCS GRYELAGLPG KSPSLASSHP 120
SLHGALDTLT HATNFLNMML QSNKSREQTV QDDLQWYQAL VRSLLEGEPS ISRAAITFST 180
ESLSTPAPQV FLQATREESR ILLQDLSSSA HHLANATLET EWFHGLRRKW RPHLHRRGSN 240
QGPRGLGHSW RRRDGLGGDR SHVKWSPPYL ECENGSYKPG WLVTLSAAFY GLQPNLVPEF 300
RGVMKVDISL QKVDIDQCSS DGWFSGTHKC HLNNSECMPI KGLGFVLGAY QCICKAGFYH 360
PRVFSVNNFQ RRGPDHHFSG STKDVSEETH VCLPCREGCP FCADDRPCFV QEDKYLRLAI 420
ISFQALCMLL DFVSMLVVYH FRKAKSIRAS GLILLETILF GSLLLYFPVV ILYFEPSTFR 480
CILLRWARLL GFATVYGTVT LKLHRVLKVF LSRTAQRIPY MTGGRVMRML AVIVLVVFWF 540
LVGWTSSMCQ NLERDILLVG QGQTSDHLTF NMCLIDRWDY MTAVAEFLFL LWGIYLCYAV 600
RTVPSAFHEP RYMAVAVHNE LIITAIFHTI RFVLASRLQP DWMLMLYFAH AHLTVTVTIG 660
LLLIPKFSHS SNNPRDDIAT EAYEDELDMG RSGSYLNSSI NSAWSEHSLD PEDIRDELKK 720
LYAQLEIYKR KKMITNNPHL QKKRCSKKGL GRSIMRRITE IPETVSRQCS KEDKEGTDHS 780
AAKGTGLVRK NPTESSGNTG RPKEESLKNR VFSLKKSHST YDHVRDQTVE SSSLPMESQE 840
EEATENSTLE SLSSKKLTQK LKEDSEAEST ESVPLVCKSA SAHNLSSEKK PGHPRTSMLQ 900
KSLSVIASAK EKTLGLAGKT QTLVMEDRAK SQKPKDRETI RKYSNSDNVE TIPNSGHMEE 960
PRKPQKSGIM KQQRVSLPTA NPDVSSGITQ IKDNFDIGEV CPWEVYDLTP GPMPSEPKAQ 1020
KHVSIAASEV EQNPASFLKE KSYHKSKATE GLYQANHKSI DKTEVCPWEI HSQSLLEDEN 1080
RLISKTPVLP GRAREENGSQ LYTTNMCAGQ YEELPHKVVA PKVENENLNQ MGDQEKQTSS 1140
SVDIIPGSCN SSNNSHQPLT SRAEVCPWEF EPLEQPNAER SVTLPASSAL SANKIPGPQK 1200 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
 GO:0072659; P:protein localization to plasma membrane; IDA:MGI.
 GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:MGI. 
Interpro
 IPR017978; GPCR_3_C. 
Pfam
 PF00003; 7tm_3 
SMART
  
PROSITE
 PS00979; G_PROTEIN_RECEP_F3_1
 PS00980; G_PROTEIN_RECEP_F3_2
 PS00981; G_PROTEIN_RECEP_F3_3
 PS50259; G_PROTEIN_RECEP_F3_4 
PRINTS