UniProt Accession

 A2ATU9_MOUSE; A2ATU9 

Genbank Protein ID

 AL928931; BX284624 

Genbank Nucleotide ID

  

Protein Name

 Histone acetyltransferase type B catalytic subunit 

Protein Synonyms/Alias

  

Gene Name

 Hat1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
6	**MAALEKFLVEYKS	acetylation	[1, 2]
12	EKFLVEYKSAVEKKL	acetylation	[2]
12	EKFLVEYKSAVEKKL	ubiquitination	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 423 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
 GO:0006348; P:chromatin silencing at telomere; IEA:InterPro. 

Interpro

 IPR016181; Acyl_CoA_acyltransferase.
 IPR019467; Hat1_N.
 IPR017380; Hist_AcTrfase_B-typ_cat-su. 

Pfam

 PF10394; Hat1_N 

SMART

  

PROSITE

  

PRINTS