UniProt Accession

 GSTT2_MOUSE; Q61133; Q61134; Q64472; Q91VB0 

Genbank Protein ID

 U48419; U48420; X98056; AK002392; AK158939; AC142499; CH466553; BC012707 

Genbank Nucleotide ID

 AAB03533.1; AAB03534.1; CAA66666.1; BAB22065.1; BAE34734.1; EDL31881.1; AAH12707.1 

Protein Name

 Glutathione S-transferase theta-2 

Protein Synonyms/Alias

 GST class-theta-2 

Gene Name

 Gstt2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
37	TRTVDILKGQHMSEQ	ubiquitination	[1]
53	SQVNCLNKVPVLKDG	ubiquitination	[1]
131	GVQVPQEKVERNRDR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. 

Sequence Annotation

 DOMAIN 2 82 GST N-terminal.
 DOMAIN 88 230 GST C-terminal.
 REGION 53 54 Glutathione binding (By similarity).
 REGION 66 67 Glutathione binding (By similarity).
 BINDING 40 40 Glutathione (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Nucleus; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 244 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0004364; F:glutathione transferase activity; ISO:MGI.
 GO:0006749; P:glutathione metabolic process; ISO:MGI. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00043; GST_C 

SMART

  

PROSITE

 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS