| Tag | Content |
|---|
| CPLM ID | CPLM-001827 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Anthranilate synthase component II |
Protein Synonyms/Alias | Glutamine amidotransferase; Anthranilate phosphoribosyltransferase |
Gene Name | trpD |
Gene Synonyms/Alias | trpGD; b1263; JW1255 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 193 | TLAWAQQKLEPANTL | acetylation | [1] | | 231 | AVVRGELKPEQLAAA | acetylation | [1] | | 243 | AAALVSMKIRGEHPN | acetylation | [1] | | 352 | VCFLFAPKYHTGFRH | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | |
Sequence Annotation | DOMAIN 3 196 Glutamine amidotransferase type-1.
REGION 202 531 Anthranilate phosphoribosyltransferase.
ACT_SITE 84 84 For GATase activity (By similarity).
ACT_SITE 170 170 For GATase activity (By similarity).
ACT_SITE 172 172 For GATase activity (By similarity). |
Keyword | Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; Direct protein sequencing; Glutamine amidotransferase; Glycosyltransferase; Lyase; Multifunctional enzyme; Reference proteome; Transferase; Tryptophan biosynthesis. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 531 AA |
Protein Sequence | MADILLLDNI DSFTYNLADQ LRSNGHNVVI YRNHIPAQTL IERLATMSNP VLMLSPGPGV 60
PSEAGCMPEL LTRLRGKLPI IGICLGHQAI VEAYGGYVGQ AGEILHGKAS SIEHDGQAMF 120
AGLTNPLPVA RYHSLVGSNI PAGLTINAHF NGMVMAVRHD ADRVCGFQFH PESILTTQGA 180
RLLEQTLAWA QQKLEPANTL QPILEKLYQA QTLSQQESHQ LFSAVVRGEL KPEQLAAALV 240
SMKIRGEHPN EIAGAATALL ENAAPFPRPD YLFADIVGTG GDGSNSINIS TASAFVAAAC 300
GLKVAKHGNR SVSSKSGSSD LLAAFGINLD MNADKSRQAL DELGVCFLFA PKYHTGFRHA 360
MPVRQQLKTR TLFNVLGPLI NPAHPPLALI GVYSPELVLP IAETLRVLGY QRAAVVHSGG 420
MDEVSLHAPT IVAELHDGEI KSYQLTAEDF GLTPYHQEQL AGGTPEENRD ILTRLLQGKG 480
DAAHEAAVAA NVAMLMRLHG HEDLQANAQT VLEVLRSGSA YDRVTALAAR G 531 |
Gene Ontology | GO:0004048; F:anthranilate phosphoribosyltransferase activity; IDA:EcoCyc. GO:0004049; F:anthranilate synthase activity; IDA:EcoCyc. GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW. GO:0000162; P:tryptophan biosynthetic process; IDA:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |