UniProt Accession

 CYC1_YEAST; P00044; D6VWL9 

Genbank Protein ID

 M37696; V01298; L26347; L36344; Z49548; X03472; BK006943 

Genbank Nucleotide ID

 AAB59344.1; CAA24605.1; AAA62856.1; AAA88751.1; CAA89576.1; CAA27189.1; DAA08835.1 

Protein Name

 Cytochrome c iso-1 

Protein Synonyms/Alias

  

Gene Name

 CYC1 

Gene Synonyms/Alias

 YJR048W; J1653 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
10	EFKAGSAKKGATLFK	ubiquitination	[1]
95	FGGLKKEKDRNDLIT	acetylation	[2]

Reference

 [1] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. 

Sequence Annotation

 METAL 24 24 Iron (heme axial ligand).
 METAL 86 86 Iron (heme axial ligand).
 BINDING 20 20 Heme (covalent).
 BINDING 23 23 Heme (covalent).
 MOD_RES 78 78 N6,N6,N6-trimethyllysine; by CTM1.
 MOD_RES 79 79 N6,N6,N6-trimethyllysine.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Methylation; Mitochondrion; Reference proteome; Respiratory chain; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 109 AA 

Protein Sequence

Gene Ontology

 GO:0005758; C:mitochondrial intermembrane space; IDA:SGD.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IDA:SGD.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IDA:SGD.
 GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IDA:SGD. 

Interpro

 IPR002327; Cyt_c_1A/1B.
 IPR009056; Cyt_c_dom.
 IPR003088; Cyt_c_I. 

Pfam

 PF00034; Cytochrom_C 

SMART

  

PROSITE

 PS51007; CYTC 

PRINTS

 PR00604; CYTCHRMECIAB.