CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013486
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ankyrin repeat domain-containing protein 54 
Protein Synonyms/Alias
  
Gene Name
 Ankrd54 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
105RRLGPTGKEVHALKRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation (By similarity). 
Sequence Annotation
 REPEAT 108 137 ANK 1.
 REPEAT 141 170 ANK 2.
 REPEAT 174 203 ANK 3.
 REPEAT 207 239 ANK 4.
 REGION 98 116 Nuclear localization signal (NLS) (By
 REGION 140 240 LYN-binding (By similarity).
 REGION 282 292 Nuclear export signal (NES) (By
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 62 62 Phosphoserine (By similarity).  
Keyword
 Acetylation; ANK repeat; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 299 AA 
Protein Sequence
MAATGGGAED ESRSGRSSSE GECAVAPEPL AEAGGLFSFA DLGAALGSGA GLPGRAVGRA 60
QSPLRYLQVL WQQDVEPRDE LRCKIPAGRL RRAARPHRRL GPTGKEVHAL KRLRDSANAN 120
DIETVQQLLE DGADPCAADD KGRTALHFAS CNGNDQIVQL LLDHGADPNQ QDGLGNTPLH 180
LAACTNHVPV ITTLLRGGAR VDALDRAGRT PLHLAKSKLN ILQEGHSQCL EAVRLEVKQI 240
IHMLREYLER LGRHEQRERL DDLCTRLQMT STKEQVDEVT DLLASFTSLS LQMQSMEKR 299 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0030496; C:midbody; ISS:UniProtKB.
 GO:0005634; C:nucleus; ISS:UniProtKB.
 GO:0019887; F:protein kinase regulator activity; IEA:Compara.
 GO:0007049; P:cell cycle; IEA:Compara.
 GO:0006913; P:nucleocytoplasmic transport; IEA:Compara.
 GO:0045648; P:positive regulation of erythrocyte differentiation; ISS:UniProtKB.
 GO:0010627; P:regulation of intracellular protein kinase cascade; ISS:UniProtKB. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom. 
Pfam
 PF12796; Ank_2 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS