UniProt Accession

 D6RHN4_MOUSE; D6RHN4 

Genbank Protein ID

 AC114905; AC120136 

Genbank Nucleotide ID

  

Protein Name

 Peroxisomal trans-2-enoyl-CoA reductase 

Protein Synonyms/Alias

  

Gene Name

 Pecr 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
5	***MGSWKTGQSYLA	acetylation	[1, 2]
5	***MGSWKTGQSYLA	succinylation	[2]
17	YLAAGLLKNQVAVVT	acetylation	[1, 2]
17	YLAAGLLKNQVAVVT	succinylation	[2]
32	GGGTGIGKAVSRELL	acetylation	[2]
32	GGGTGIGKAVSRELL	succinylation	[2]
32	GGGTGIGKAVSRELL	ubiquitination	[3]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 90 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005777; C:peroxisome; ISA:MGI.
 GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; ISA:MGI.
 GO:0030497; P:fatty acid elongation; ISA:MGI. 

Interpro

 IPR002198; DH_sc/Rdtase_SDR.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF00106; adh_short 

SMART

  

PROSITE

  

PRINTS