UniProt Accession

 F5H853_HUMAN; F5H853 

Genbank Protein ID

 Z97832 

Genbank Nucleotide ID

  

Protein Name

 Defensin-6 

Protein Synonyms/Alias

  

Gene Name

 DEF6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
63	IRLQAEGKTSLHKDL	ubiquitination	[1]
88	RERRRAAKEEELLRL	ubiquitination	[1]
102	LQQLQEEKERKLQEL	ubiquitination	[1, 2]
105	LQEEKERKLQELELL	ubiquitination	[1, 2]
174	ARQRQRIKELEEMQQ	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005543; F:phospholipid binding; IEA:InterPro. 

Interpro

 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 

Pfam

  

SMART

  

PROSITE

 PS50003; PH_DOMAIN 

PRINTS