CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012917
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S21-B 
Protein Synonyms/Alias
 S26; YS25 
Gene Name
 RPS21B 
Gene Synonyms/Alias
 RPS25B; RPS26B; YJL136C; J0664 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
5***MENDKGQLVELYacetylation[1]
38SVQINVAKVDEEGRAubiquitination[2]
80AQNDGLLKNVWSYSRubiquitination[2]
Reference
 [1] Preparative peptide isoelectric focusing as a tool for improving the identification of lysine-acetylated peptides from complex mixtures.
 Xie H, Bandhakavi S, Roe MR, Griffin TJ.
 J Proteome Res. 2007 May;6(5):2019-26. [PMID: 17397211]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
 Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability. 
Sequence Annotation
 MOD_RES 1 1 N-acetylmethionine.  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 87 AA 
Protein Sequence
MENDKGQLVE LYVPRKCSAT NRIIKADDHA SVQINVAKVD EEGRAIPGEY ITYALSGYVR 60
SRGESDDSLN RLAQNDGLLK NVWSYSR 87 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; IDA:SGD.
 GO:0002181; P:cytoplasmic translation; IC:SGD.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.
 GO:0006414; P:translational elongation; IBA:RefGenome. 
Interpro
 IPR001931; Ribosomal_S21e.
 IPR018279; Ribosomal_S21e_CS. 
Pfam
 PF01249; Ribosomal_S21e 
SMART
  
PROSITE
 PS00996; RIBOSOMAL_S21E 
PRINTS